Super-resolution architecture of mammalian centriole distal appendages reveals distinct blade and matrix functional components
Distal appendages (DAPs) at the cilia base mediate membrane docking during ciliogenesis. Here the authors use super-resolution microscopy to map 16 centriole distal end components, revealing the structure of the backbone of the DAP, as well as a previously undescribed distal appendage matrix.
Guardado en:
Autores principales: | T. Tony Yang, Weng Man Chong, Won-Jing Wang, Gregory Mazo, Barbara Tanos, Zhengmin Chen, Thi Minh Nguyet Tran, Yi-De Chen, Rueyhung Roc Weng, Chia-En Huang, Wann-Neng Jane, Meng-Fu Bryan Tsou, Jung-Chi Liao |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2018
|
Materias: | |
Acceso en línea: | https://doaj.org/article/fc52cee4ed1b40db955022dc053ae118 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
High-resolution characterization of centriole distal appendage morphology and dynamics by correlative STORM and electron microscopy
por: Mathew Bowler, et al.
Publicado: (2019) -
Hierarchical assembly of centriole subdistal appendages via centrosome binding proteins CCDC120 and CCDC68
por: Ning Huang, et al.
Publicado: (2017) -
The Role of Centrosome Distal Appendage Proteins (DAPs) in Nephronophthisis and Ciliogenesis
por: Fatma Mansour, et al.
Publicado: (2021) -
Coping with centriole loss: pericentriolar material maintenance after centriole degeneration
por: Carla M. C. Abreu, et al.
Publicado: (2021) -
Over-elongation of centrioles in cancer promotes centriole amplification and chromosome missegregation
por: Gaëlle Marteil, et al.
Publicado: (2018)