Exploration of collagen cavitation based on peptide electrolysis

Abstract Electrochemical modification of animal skin is a new material preparation method and new direction of research exploration. In this study, under the action of the electric field using NaCl as the supporting electrolyte, the effect of electrolysis on Glycyl-glycine(GlyGl), gelatin(Gel) and T...

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Autores principales:	Rui Zhai, Hui Chen, Zhihua Shan
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/fc53b00145bb42e0a7b226e327f743a4
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spelling	oai:doaj.org-article:fc53b00145bb42e0a7b226e327f743a42021-12-02T18:53:09ZExploration of collagen cavitation based on peptide electrolysis10.1038/s41598-021-96533-y2045-2322https://doaj.org/article/fc53b00145bb42e0a7b226e327f743a42021-08-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-96533-yhttps://doaj.org/toc/2045-2322Abstract Electrochemical modification of animal skin is a new material preparation method and new direction of research exploration. In this study, under the action of the electric field using NaCl as the supporting electrolyte, the effect of electrolysis on Glycyl-glycine(GlyGl), gelatin(Gel) and Three-dimensional rawhide collagen(3DC) were determined. The amino group of GlyGl is quickly eliminated within the anode region by electrolysis isolated by an anion exchange membrane. Using the same method, it was found that the molecular weight of Gel and the isoelectric point of the Gel decreased, and the viscosity and transparency of the Gel solution obviously changed. The electrolytic dissolution and structural changes of 3DC were further investigated. The results of TOC and TN showed that the organic matter in 3DC was dissolved by electrolysis, and the tissue cavitation was obvious. A new approach for the preparation of collagen-based multi-pore biomaterials by electrochemical method was explored.Rui ZhaiHui ChenZhihua ShanNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Rui Zhai Hui Chen Zhihua Shan Exploration of collagen cavitation based on peptide electrolysis
description	Abstract Electrochemical modification of animal skin is a new material preparation method and new direction of research exploration. In this study, under the action of the electric field using NaCl as the supporting electrolyte, the effect of electrolysis on Glycyl-glycine(GlyGl), gelatin(Gel) and Three-dimensional rawhide collagen(3DC) were determined. The amino group of GlyGl is quickly eliminated within the anode region by electrolysis isolated by an anion exchange membrane. Using the same method, it was found that the molecular weight of Gel and the isoelectric point of the Gel decreased, and the viscosity and transparency of the Gel solution obviously changed. The electrolytic dissolution and structural changes of 3DC were further investigated. The results of TOC and TN showed that the organic matter in 3DC was dissolved by electrolysis, and the tissue cavitation was obvious. A new approach for the preparation of collagen-based multi-pore biomaterials by electrochemical method was explored.
format	article
author	Rui Zhai Hui Chen Zhihua Shan
author_facet	Rui Zhai Hui Chen Zhihua Shan
author_sort	Rui Zhai
title	Exploration of collagen cavitation based on peptide electrolysis
title_short	Exploration of collagen cavitation based on peptide electrolysis
title_full	Exploration of collagen cavitation based on peptide electrolysis
title_fullStr	Exploration of collagen cavitation based on peptide electrolysis
title_full_unstemmed	Exploration of collagen cavitation based on peptide electrolysis
title_sort	exploration of collagen cavitation based on peptide electrolysis
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/fc53b00145bb42e0a7b226e327f743a4
work_keys_str_mv	AT ruizhai explorationofcollagencavitationbasedonpeptideelectrolysis AT huichen explorationofcollagencavitationbasedonpeptideelectrolysis AT zhihuashan explorationofcollagencavitationbasedonpeptideelectrolysis
_version_	1718377364331692032

Exploration of collagen cavitation based on peptide electrolysis

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