Growth and development of children under 5 years of age with tetralogy of Fallot in a Chinese population

Abstract Congenital Heart Defects (CHDs) are associated with different patterns of malnutrition and growth retardation, which may vary worldwide and need to be evaluated according to local conditions. Although tetralogy of Fallot (TOF) is one of the first described CHDs, the etiology outcomes in gro...

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Autores principales:	Xin Li, Jin Zhu, Jun An, Yuqing Wang, Yili Wu, Xuezhi Li
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/fc61e7d3096e4e11bbb099b509a38dab
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spelling	oai:doaj.org-article:fc61e7d3096e4e11bbb099b509a38dab2021-12-02T15:23:07ZGrowth and development of children under 5 years of age with tetralogy of Fallot in a Chinese population10.1038/s41598-021-93726-32045-2322https://doaj.org/article/fc61e7d3096e4e11bbb099b509a38dab2021-07-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-93726-3https://doaj.org/toc/2045-2322Abstract Congenital Heart Defects (CHDs) are associated with different patterns of malnutrition and growth retardation, which may vary worldwide and need to be evaluated according to local conditions. Although tetralogy of Fallot (TOF) is one of the first described CHDs, the etiology outcomes in growth and development of TOF in early age child is still unclear in most cases. This study was designed to investigate the growth retardation status of Chinese pediatric TOF patients under 5 years old. The body height, body weight and body mass index (BMI) of 262 pediatric patients (138 boys and 124 girls) who underwent corrective surgery for TOF between 2014 and 2018 were measured using conventional methods. The average body height, body weight and BMI of the patients were significantly lower than WHO Child Growth Standards, while the most affected was body height. Meanwhile, higher stunting frequency and greater deterioration of both the body height and weight happened in elder age (aged 13–60 months) rather than in infant stage (aged 0–12 months) among these patients. Our results confirmed that intervention should be given at early age to prevent the growth retardation of TOF patients getting severer.Xin LiJin ZhuJun AnYuqing WangYili WuXuezhi LiNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Xin Li Jin Zhu Jun An Yuqing Wang Yili Wu Xuezhi Li Growth and development of children under 5 years of age with tetralogy of Fallot in a Chinese population
description	Abstract Congenital Heart Defects (CHDs) are associated with different patterns of malnutrition and growth retardation, which may vary worldwide and need to be evaluated according to local conditions. Although tetralogy of Fallot (TOF) is one of the first described CHDs, the etiology outcomes in growth and development of TOF in early age child is still unclear in most cases. This study was designed to investigate the growth retardation status of Chinese pediatric TOF patients under 5 years old. The body height, body weight and body mass index (BMI) of 262 pediatric patients (138 boys and 124 girls) who underwent corrective surgery for TOF between 2014 and 2018 were measured using conventional methods. The average body height, body weight and BMI of the patients were significantly lower than WHO Child Growth Standards, while the most affected was body height. Meanwhile, higher stunting frequency and greater deterioration of both the body height and weight happened in elder age (aged 13–60 months) rather than in infant stage (aged 0–12 months) among these patients. Our results confirmed that intervention should be given at early age to prevent the growth retardation of TOF patients getting severer.
format	article
author	Xin Li Jin Zhu Jun An Yuqing Wang Yili Wu Xuezhi Li
author_facet	Xin Li Jin Zhu Jun An Yuqing Wang Yili Wu Xuezhi Li
author_sort	Xin Li
title	Growth and development of children under 5 years of age with tetralogy of Fallot in a Chinese population
title_short	Growth and development of children under 5 years of age with tetralogy of Fallot in a Chinese population
title_full	Growth and development of children under 5 years of age with tetralogy of Fallot in a Chinese population
title_fullStr	Growth and development of children under 5 years of age with tetralogy of Fallot in a Chinese population
title_full_unstemmed	Growth and development of children under 5 years of age with tetralogy of Fallot in a Chinese population
title_sort	growth and development of children under 5 years of age with tetralogy of fallot in a chinese population
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/fc61e7d3096e4e11bbb099b509a38dab
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_version_	1718387364215128064

Growth and development of children under 5 years of age with tetralogy of Fallot in a Chinese population

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