Liquid biopsy-based single-cell metabolic phenotyping of lung cancer patients for informative diagnostics

Non-invasive methods to predict treatment response are urgently needed. Here in lung cancer, the authors develop a single-cell on-chip cytometry method to metabolically phenotype disseminated tumor cells, revealing metabolic heterogeneity and predictors of therapy response and survival.

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Autores principales: Ziming Li, Zhuo Wang, Yin Tang, Xiang Lu, Jie Chen, Yu Dong, Baojun Wu, Chunying Wang, Liu Yang, Zhili Guo, Min Xue, Shun Lu, Wei Wei, Qihui Shi
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/fc6306e74458427db8cad26bd5b3ccb6
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spelling oai:doaj.org-article:fc6306e74458427db8cad26bd5b3ccb62021-12-02T15:35:09ZLiquid biopsy-based single-cell metabolic phenotyping of lung cancer patients for informative diagnostics10.1038/s41467-019-11808-32041-1723https://doaj.org/article/fc6306e74458427db8cad26bd5b3ccb62019-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11808-3https://doaj.org/toc/2041-1723Non-invasive methods to predict treatment response are urgently needed. Here in lung cancer, the authors develop a single-cell on-chip cytometry method to metabolically phenotype disseminated tumor cells, revealing metabolic heterogeneity and predictors of therapy response and survival.Ziming LiZhuo WangYin TangXiang LuJie ChenYu DongBaojun WuChunying WangLiu YangZhili GuoMin XueShun LuWei WeiQihui ShiNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Ziming Li
Zhuo Wang
Yin Tang
Xiang Lu
Jie Chen
Yu Dong
Baojun Wu
Chunying Wang
Liu Yang
Zhili Guo
Min Xue
Shun Lu
Wei Wei
Qihui Shi
Liquid biopsy-based single-cell metabolic phenotyping of lung cancer patients for informative diagnostics
description Non-invasive methods to predict treatment response are urgently needed. Here in lung cancer, the authors develop a single-cell on-chip cytometry method to metabolically phenotype disseminated tumor cells, revealing metabolic heterogeneity and predictors of therapy response and survival.
format article
author Ziming Li
Zhuo Wang
Yin Tang
Xiang Lu
Jie Chen
Yu Dong
Baojun Wu
Chunying Wang
Liu Yang
Zhili Guo
Min Xue
Shun Lu
Wei Wei
Qihui Shi
author_facet Ziming Li
Zhuo Wang
Yin Tang
Xiang Lu
Jie Chen
Yu Dong
Baojun Wu
Chunying Wang
Liu Yang
Zhili Guo
Min Xue
Shun Lu
Wei Wei
Qihui Shi
author_sort Ziming Li
title Liquid biopsy-based single-cell metabolic phenotyping of lung cancer patients for informative diagnostics
title_short Liquid biopsy-based single-cell metabolic phenotyping of lung cancer patients for informative diagnostics
title_full Liquid biopsy-based single-cell metabolic phenotyping of lung cancer patients for informative diagnostics
title_fullStr Liquid biopsy-based single-cell metabolic phenotyping of lung cancer patients for informative diagnostics
title_full_unstemmed Liquid biopsy-based single-cell metabolic phenotyping of lung cancer patients for informative diagnostics
title_sort liquid biopsy-based single-cell metabolic phenotyping of lung cancer patients for informative diagnostics
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/fc6306e74458427db8cad26bd5b3ccb6
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