Liquid biopsy-based single-cell metabolic phenotyping of lung cancer patients for informative diagnostics
Non-invasive methods to predict treatment response are urgently needed. Here in lung cancer, the authors develop a single-cell on-chip cytometry method to metabolically phenotype disseminated tumor cells, revealing metabolic heterogeneity and predictors of therapy response and survival.
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Nature Portfolio
2019
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oai:doaj.org-article:fc6306e74458427db8cad26bd5b3ccb62021-12-02T15:35:09ZLiquid biopsy-based single-cell metabolic phenotyping of lung cancer patients for informative diagnostics10.1038/s41467-019-11808-32041-1723https://doaj.org/article/fc6306e74458427db8cad26bd5b3ccb62019-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11808-3https://doaj.org/toc/2041-1723Non-invasive methods to predict treatment response are urgently needed. Here in lung cancer, the authors develop a single-cell on-chip cytometry method to metabolically phenotype disseminated tumor cells, revealing metabolic heterogeneity and predictors of therapy response and survival.Ziming LiZhuo WangYin TangXiang LuJie ChenYu DongBaojun WuChunying WangLiu YangZhili GuoMin XueShun LuWei WeiQihui ShiNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-16 (2019) |
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Science Q Ziming Li Zhuo Wang Yin Tang Xiang Lu Jie Chen Yu Dong Baojun Wu Chunying Wang Liu Yang Zhili Guo Min Xue Shun Lu Wei Wei Qihui Shi Liquid biopsy-based single-cell metabolic phenotyping of lung cancer patients for informative diagnostics |
description |
Non-invasive methods to predict treatment response are urgently needed. Here in lung cancer, the authors develop a single-cell on-chip cytometry method to metabolically phenotype disseminated tumor cells, revealing metabolic heterogeneity and predictors of therapy response and survival. |
format |
article |
author |
Ziming Li Zhuo Wang Yin Tang Xiang Lu Jie Chen Yu Dong Baojun Wu Chunying Wang Liu Yang Zhili Guo Min Xue Shun Lu Wei Wei Qihui Shi |
author_facet |
Ziming Li Zhuo Wang Yin Tang Xiang Lu Jie Chen Yu Dong Baojun Wu Chunying Wang Liu Yang Zhili Guo Min Xue Shun Lu Wei Wei Qihui Shi |
author_sort |
Ziming Li |
title |
Liquid biopsy-based single-cell metabolic phenotyping of lung cancer patients for informative diagnostics |
title_short |
Liquid biopsy-based single-cell metabolic phenotyping of lung cancer patients for informative diagnostics |
title_full |
Liquid biopsy-based single-cell metabolic phenotyping of lung cancer patients for informative diagnostics |
title_fullStr |
Liquid biopsy-based single-cell metabolic phenotyping of lung cancer patients for informative diagnostics |
title_full_unstemmed |
Liquid biopsy-based single-cell metabolic phenotyping of lung cancer patients for informative diagnostics |
title_sort |
liquid biopsy-based single-cell metabolic phenotyping of lung cancer patients for informative diagnostics |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/fc6306e74458427db8cad26bd5b3ccb6 |
work_keys_str_mv |
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