Astrocyte GluN2C NMDA receptors control basal synaptic strengths of hippocampal CA1 pyramidal neurons in the stratum radiatum

Astrocyte GluN2C NMDA receptors control basal synaptic strengths of hippocampal CA1 pyramidal neurons in the stratum radiatum

Experience-dependent plasticity is a key feature of brain synapses for which neuronal N-Methyl-D-Aspartate receptors (NMDARs) play a major role, from developmental circuit refinement to learning and memory. Astrocytes also express NMDARs, although their exact function has remained controversial. Her...

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Bibliographic Details
Main Authors: Peter H Chipman, Chi Chung Alan Fung, Alejandra Pazo Fernandez, Abhilash Sawant, Angelo Tedoldi, Atsushi Kawai, Sunita Ghimire Gautam, Mizuki Kurosawa, Manabu Abe, Kenji Sakimura, Tomoki Fukai, Yukiko Goda
Format: article
Language:EN
Published: eLife Sciences Publications Ltd 2021
Subjects:
basal synaptic strength
hippocampus
astrocytes
NMDA receptors
GluN2C
stratum radiatum
Medicine
R
Science
Q
Biology (General)
QH301-705.5
Online Access:https://doaj.org/article/fc6c9c03fd6442bd9963a5bad97386fc
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https://doaj.org/article/fc6c9c03fd6442bd9963a5bad97386fc

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