Reactivity of an organism at hypertrophic skin scars

The aim of the research was to assess the reactivity of female organism with hypertrophic scars. 42 women of 16-35years were examined on the 5-7th day of the menstrual cycle, 17 of them had normotrophic and 25 - hypertrophic scars. The quality of scars (according to the clinical and morphological ch...

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Autores principales: M. V. Kobets, L. S. Vasiljeva, I. M. Mikhalevich, V. V. Malyshev
Formato: article
Lenguaje:RU
Publicado: Scientific Сentre for Family Health and Human Reproduction Problems 2014
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Acceso en línea:https://doaj.org/article/fc72d7c7dfce41e692bfc5a0eec6b567
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spelling oai:doaj.org-article:fc72d7c7dfce41e692bfc5a0eec6b5672021-11-23T06:14:30ZReactivity of an organism at hypertrophic skin scars2541-94202587-9596https://doaj.org/article/fc72d7c7dfce41e692bfc5a0eec6b5672014-05-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/1759https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596The aim of the research was to assess the reactivity of female organism with hypertrophic scars. 42 women of 16-35years were examined on the 5-7th day of the menstrual cycle, 17 of them had normotrophic and 25 - hypertrophic scars. The quality of scars (according to the clinical and morphological characteristics), white blood cells, blood lipids, hormonal and immune status were assessed. Non-parametric Mann - Whitney U-test and discriminant analysis were used at statistical processing of the results. Average values and standard deviations were also calculated for interpreting the results of quantitative indications. As the result of discriminant analysis the most informative indicators of reactivity of an organism that allow to differentiate patients of the studied groups were defined for patients with normotrophic and hypertrophic scars. It was concluded that the imbalance of steroid hormones (progesterone, cortisol, testosterone, estrogen) was important in the etiopathogenesis of hypertrophic scars.M. V. KobetsL. S. VasiljevaI. M. MikhalevichV. V. MalyshevScientific Сentre for Family Health and Human Reproduction Problemsarticlehypertrophic scarsfibrosissteroid hormonesScienceQRUActa Biomedica Scientifica, Vol 0, Iss 3, Pp 35-40 (2014)
institution DOAJ
collection DOAJ
language RU
topic hypertrophic scars
fibrosis
steroid hormones
Science
Q
spellingShingle hypertrophic scars
fibrosis
steroid hormones
Science
Q
M. V. Kobets
L. S. Vasiljeva
I. M. Mikhalevich
V. V. Malyshev
Reactivity of an organism at hypertrophic skin scars
description The aim of the research was to assess the reactivity of female organism with hypertrophic scars. 42 women of 16-35years were examined on the 5-7th day of the menstrual cycle, 17 of them had normotrophic and 25 - hypertrophic scars. The quality of scars (according to the clinical and morphological characteristics), white blood cells, blood lipids, hormonal and immune status were assessed. Non-parametric Mann - Whitney U-test and discriminant analysis were used at statistical processing of the results. Average values and standard deviations were also calculated for interpreting the results of quantitative indications. As the result of discriminant analysis the most informative indicators of reactivity of an organism that allow to differentiate patients of the studied groups were defined for patients with normotrophic and hypertrophic scars. It was concluded that the imbalance of steroid hormones (progesterone, cortisol, testosterone, estrogen) was important in the etiopathogenesis of hypertrophic scars.
format article
author M. V. Kobets
L. S. Vasiljeva
I. M. Mikhalevich
V. V. Malyshev
author_facet M. V. Kobets
L. S. Vasiljeva
I. M. Mikhalevich
V. V. Malyshev
author_sort M. V. Kobets
title Reactivity of an organism at hypertrophic skin scars
title_short Reactivity of an organism at hypertrophic skin scars
title_full Reactivity of an organism at hypertrophic skin scars
title_fullStr Reactivity of an organism at hypertrophic skin scars
title_full_unstemmed Reactivity of an organism at hypertrophic skin scars
title_sort reactivity of an organism at hypertrophic skin scars
publisher Scientific Сentre for Family Health and Human Reproduction Problems
publishDate 2014
url https://doaj.org/article/fc72d7c7dfce41e692bfc5a0eec6b567
work_keys_str_mv AT mvkobets reactivityofanorganismathypertrophicskinscars
AT lsvasiljeva reactivityofanorganismathypertrophicskinscars
AT immikhalevich reactivityofanorganismathypertrophicskinscars
AT vvmalyshev reactivityofanorganismathypertrophicskinscars
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