Preparation and physicochemical characterization of sildenafil cocrystals

Sildenafil is a specific inhibitor of the phosphodiesterase type 5 (PDE-5) enzyme that protects cyclic guanosine monophosphate from breakdown by PDE-5. It is a biopharmaceutical categorization system Class II medication with low bioavailability because it is almost insoluble in water. The objectives...

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Bibliographic Details
Main Authors: Somchai Sawatdee, Apichart Atipairin, Supitchaya Rakkummerd, Onsinee Suriyaphol, David J Harding, Poowadon Muenraya, Phimphaka Harding
Format: article
Language:EN
Published: Wolters Kluwer Medknow Publications 2021
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Online Access:https://doaj.org/article/fc7af6e60a36430497abad6a089bd338
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