Microchannel network hydrogel induced ischemic blood perfusion connection

Restoration of blood flow to damaged sites has commonly involved treatment with pro-angiogenic molecules but these have undesired side effects. Here the authors present a microchannel-patterned gelatin hydrogel that is able to rescue mouse and porcine models of hindlimb ischemia.

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Autores principales: Jung Bok Lee, Dae-Hyun Kim, Jeong-Kee Yoon, Dan Bi Park, Hye-Seon Kim, Young Min Shin, Wooyeol Baek, Mi-Lan Kang, Hyun Jung Kim, Hak-Joon Sung
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/fc7ff77ebe6443e8b497c3e4507d759c
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spelling oai:doaj.org-article:fc7ff77ebe6443e8b497c3e4507d759c2021-12-02T14:41:13ZMicrochannel network hydrogel induced ischemic blood perfusion connection10.1038/s41467-020-14480-02041-1723https://doaj.org/article/fc7ff77ebe6443e8b497c3e4507d759c2020-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-14480-0https://doaj.org/toc/2041-1723Restoration of blood flow to damaged sites has commonly involved treatment with pro-angiogenic molecules but these have undesired side effects. Here the authors present a microchannel-patterned gelatin hydrogel that is able to rescue mouse and porcine models of hindlimb ischemia.Jung Bok LeeDae-Hyun KimJeong-Kee YoonDan Bi ParkHye-Seon KimYoung Min ShinWooyeol BaekMi-Lan KangHyun Jung KimHak-Joon SungNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Jung Bok Lee
Dae-Hyun Kim
Jeong-Kee Yoon
Dan Bi Park
Hye-Seon Kim
Young Min Shin
Wooyeol Baek
Mi-Lan Kang
Hyun Jung Kim
Hak-Joon Sung
Microchannel network hydrogel induced ischemic blood perfusion connection
description Restoration of blood flow to damaged sites has commonly involved treatment with pro-angiogenic molecules but these have undesired side effects. Here the authors present a microchannel-patterned gelatin hydrogel that is able to rescue mouse and porcine models of hindlimb ischemia.
format article
author Jung Bok Lee
Dae-Hyun Kim
Jeong-Kee Yoon
Dan Bi Park
Hye-Seon Kim
Young Min Shin
Wooyeol Baek
Mi-Lan Kang
Hyun Jung Kim
Hak-Joon Sung
author_facet Jung Bok Lee
Dae-Hyun Kim
Jeong-Kee Yoon
Dan Bi Park
Hye-Seon Kim
Young Min Shin
Wooyeol Baek
Mi-Lan Kang
Hyun Jung Kim
Hak-Joon Sung
author_sort Jung Bok Lee
title Microchannel network hydrogel induced ischemic blood perfusion connection
title_short Microchannel network hydrogel induced ischemic blood perfusion connection
title_full Microchannel network hydrogel induced ischemic blood perfusion connection
title_fullStr Microchannel network hydrogel induced ischemic blood perfusion connection
title_full_unstemmed Microchannel network hydrogel induced ischemic blood perfusion connection
title_sort microchannel network hydrogel induced ischemic blood perfusion connection
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/fc7ff77ebe6443e8b497c3e4507d759c
work_keys_str_mv AT jungboklee microchannelnetworkhydrogelinducedischemicbloodperfusionconnection
AT daehyunkim microchannelnetworkhydrogelinducedischemicbloodperfusionconnection
AT jeongkeeyoon microchannelnetworkhydrogelinducedischemicbloodperfusionconnection
AT danbipark microchannelnetworkhydrogelinducedischemicbloodperfusionconnection
AT hyeseonkim microchannelnetworkhydrogelinducedischemicbloodperfusionconnection
AT youngminshin microchannelnetworkhydrogelinducedischemicbloodperfusionconnection
AT wooyeolbaek microchannelnetworkhydrogelinducedischemicbloodperfusionconnection
AT milankang microchannelnetworkhydrogelinducedischemicbloodperfusionconnection
AT hyunjungkim microchannelnetworkhydrogelinducedischemicbloodperfusionconnection
AT hakjoonsung microchannelnetworkhydrogelinducedischemicbloodperfusionconnection
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