The CoREST/REST Repressor Is both Necessary and Inimical for Expression of Herpes Simplex Virus Genes

ABSTRACT Herpes simplex virus type 1 encodes three sets of genes, α, β, and γ, whose expression is sequentially ordered in a cascade fashion. The transactivators of α genes comprise virion protein 16 (VP16) and the cellular proteins octamer binding protein 1 (Oct1) and host factor 1 (HCF1). Efficien...

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Autores principales: Guoying Zhou, Du Te, Bernard Roizman
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2011
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Acceso en línea:https://doaj.org/article/fc80b9e1323e472ca78ecb7e7a19b0c2
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