Adherence to antiretroviral therapy in Nigeria: an overview of research studies and implications for policy and practice

Emmanuel Monjok1, Andrea Smesny1, Ita B Okokon2, Osaro Mgbere3, E James Essien11Institute of Community Health, University of Houston, Texas Medical Center, Houston Texas 77030, USA; 2Department of Family Medicine, University of Calabar Teaching Hospital, Calabar, Nigeria; 3Bureau of Epidemiology, Ho...

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Autores principales:	Emmanuel Monjok, Andrea Smesny, Ita B Okokon, et al
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2010
Materias:	Immunologic diseases. Allergy RC581-607
Acceso en línea:	https://doaj.org/article/fc90a8cc8a0f412b8b43645e5ec03126
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spelling	oai:doaj.org-article:fc90a8cc8a0f412b8b43645e5ec031262021-12-02T08:36:09ZAdherence to antiretroviral therapy in Nigeria: an overview of research studies and implications for policy and practice1179-1373https://doaj.org/article/fc90a8cc8a0f412b8b43645e5ec031262010-03-01T00:00:00Zhttp://www.dovepress.com/adherence-to-antiretroviral-therapy-in-nigeria-an-overview-of-research-a4172https://doaj.org/toc/1179-1373Emmanuel Monjok1, Andrea Smesny1, Ita B Okokon2, Osaro Mgbere3, E James Essien11Institute of Community Health, University of Houston, Texas Medical Center, Houston Texas 77030, USA; 2Department of Family Medicine, University of Calabar Teaching Hospital, Calabar, Nigeria; 3Bureau of Epidemiology, Houston Department of Health and Human Services, Houston, Texas 77054, USAAbstract: Both Human Immunodeficiency Virus (HIV) infection and AIDS remain major public health crises in Nigeria, a country which harbors more people living with HIV/AIDS than any country in the world, with the exception of South Africa and India. In response to the HIV pandemic, global and international health initiatives have targeted several countries, including Nigeria, for the expansion of antiretroviral therapy (ART) programs for the increasing number of affected patients. The success of these expanded ART initiatives depends on the treated individual&rsquo;s continual adherence to antiretroviral (ARV) drugs. Thirteen peer-reviewed studies concerning adherence to ART in Nigeria were reviewed with very few pediatric and adolescent studies being found. Methodologies of adherence measurement were analyzed and reasons for nonadherence were identified in the geopolitical zones in the federal republic of Nigeria. The results of the literature review indicate that adherence to ART is mixed (both high and low adherence) with patient self-recall identified as the common method of assessment. The most common reasons identified for patient nonadherence include the cost of therapy (even when the drugs are heavily subsidized), medication side effects, nonavailability of ARV drugs, and the stigma of taking the drugs. This manuscript highlights the policy and practice implications from these studies and provides recommendations for future ART program management.Keywords: adherence, antiretroviral therapy (ART), HIV, PLWHA, Nigeria Emmanuel MonjokAndrea SmesnyIta B Okokonet alDove Medical PressarticleImmunologic diseases. AllergyRC581-607ENHIV/AIDS: Research and Palliative Care, Vol 2010, Iss default, Pp 69-76 (2010)
institution	DOAJ
collection	DOAJ
language	EN
topic	Immunologic diseases. Allergy RC581-607
spellingShingle	Immunologic diseases. Allergy RC581-607 Emmanuel Monjok Andrea Smesny Ita B Okokon et al Adherence to antiretroviral therapy in Nigeria: an overview of research studies and implications for policy and practice
description	Emmanuel Monjok1, Andrea Smesny1, Ita B Okokon2, Osaro Mgbere3, E James Essien11Institute of Community Health, University of Houston, Texas Medical Center, Houston Texas 77030, USA; 2Department of Family Medicine, University of Calabar Teaching Hospital, Calabar, Nigeria; 3Bureau of Epidemiology, Houston Department of Health and Human Services, Houston, Texas 77054, USAAbstract: Both Human Immunodeficiency Virus (HIV) infection and AIDS remain major public health crises in Nigeria, a country which harbors more people living with HIV/AIDS than any country in the world, with the exception of South Africa and India. In response to the HIV pandemic, global and international health initiatives have targeted several countries, including Nigeria, for the expansion of antiretroviral therapy (ART) programs for the increasing number of affected patients. The success of these expanded ART initiatives depends on the treated individual&rsquo;s continual adherence to antiretroviral (ARV) drugs. Thirteen peer-reviewed studies concerning adherence to ART in Nigeria were reviewed with very few pediatric and adolescent studies being found. Methodologies of adherence measurement were analyzed and reasons for nonadherence were identified in the geopolitical zones in the federal republic of Nigeria. The results of the literature review indicate that adherence to ART is mixed (both high and low adherence) with patient self-recall identified as the common method of assessment. The most common reasons identified for patient nonadherence include the cost of therapy (even when the drugs are heavily subsidized), medication side effects, nonavailability of ARV drugs, and the stigma of taking the drugs. This manuscript highlights the policy and practice implications from these studies and provides recommendations for future ART program management.Keywords: adherence, antiretroviral therapy (ART), HIV, PLWHA, Nigeria
format	article
author	Emmanuel Monjok Andrea Smesny Ita B Okokon et al
author_facet	Emmanuel Monjok Andrea Smesny Ita B Okokon et al
author_sort	Emmanuel Monjok
title	Adherence to antiretroviral therapy in Nigeria: an overview of research studies and implications for policy and practice
title_short	Adherence to antiretroviral therapy in Nigeria: an overview of research studies and implications for policy and practice
title_full	Adherence to antiretroviral therapy in Nigeria: an overview of research studies and implications for policy and practice
title_fullStr	Adherence to antiretroviral therapy in Nigeria: an overview of research studies and implications for policy and practice
title_full_unstemmed	Adherence to antiretroviral therapy in Nigeria: an overview of research studies and implications for policy and practice
title_sort	adherence to antiretroviral therapy in nigeria: an overview of research studies and implications for policy and practice
publisher	Dove Medical Press
publishDate	2010
url	https://doaj.org/article/fc90a8cc8a0f412b8b43645e5ec03126
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Adherence to antiretroviral therapy in Nigeria: an overview of research studies and implications for policy and practice

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