Long noncoding RNA SAM promotes myoblast proliferation through stabilizing Sugt1 and facilitating kinetochore assembly

Long noncoding RNA SAM promotes myoblast proliferation through stabilizing Sugt1 and facilitating kinetochore assembly

Long noncoding RNA SAM (Sugt1 associated muscle) is upregulated in the proliferating myoblast cells. Here the authors investigate SAM knockout mice and suggest that SAM binds and stabilizes Sugt1, a co-chaperone protein that regulates kinetochore assembly.

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Autores principales: Yuying Li, Jie Yuan, Fengyuan Chen, Suyang Zhang, Yu Zhao, Xiaona Chen, Leina Lu, Liang Zhou, Ching Yan Chu, Hao Sun, Huating Wang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/fc9b05f5e91e40be8b3b91dd506c1ed7
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spelling oai:doaj.org-article:fc9b05f5e91e40be8b3b91dd506c1ed72021-12-02T15:02:30ZLong noncoding RNA SAM promotes myoblast proliferation through stabilizing Sugt1 and facilitating kinetochore assembly10.1038/s41467-020-16553-62041-1723https://doaj.org/article/fc9b05f5e91e40be8b3b91dd506c1ed72020-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16553-6https://doaj.org/toc/2041-1723Long noncoding RNA SAM (Sugt1 associated muscle) is upregulated in the proliferating myoblast cells. Here the authors investigate SAM knockout mice and suggest that SAM binds and stabilizes Sugt1, a co-chaperone protein that regulates kinetochore assembly.Yuying LiJie YuanFengyuan ChenSuyang ZhangYu ZhaoXiaona ChenLeina LuLiang ZhouChing Yan ChuHao SunHuating WangNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Yuying Li
Jie Yuan
Fengyuan Chen
Suyang Zhang
Yu Zhao
Xiaona Chen
Leina Lu
Liang Zhou
Ching Yan Chu
Hao Sun
Huating Wang
Long noncoding RNA SAM promotes myoblast proliferation through stabilizing Sugt1 and facilitating kinetochore assembly
description Long noncoding RNA SAM (Sugt1 associated muscle) is upregulated in the proliferating myoblast cells. Here the authors investigate SAM knockout mice and suggest that SAM binds and stabilizes Sugt1, a co-chaperone protein that regulates kinetochore assembly.
format article
author Yuying Li
Jie Yuan
Fengyuan Chen
Suyang Zhang
Yu Zhao
Xiaona Chen
Leina Lu
Liang Zhou
Ching Yan Chu
Hao Sun
Huating Wang
author_facet Yuying Li
Jie Yuan
Fengyuan Chen
Suyang Zhang
Yu Zhao
Xiaona Chen
Leina Lu
Liang Zhou
Ching Yan Chu
Hao Sun
Huating Wang
author_sort Yuying Li
title Long noncoding RNA SAM promotes myoblast proliferation through stabilizing Sugt1 and facilitating kinetochore assembly
title_short Long noncoding RNA SAM promotes myoblast proliferation through stabilizing Sugt1 and facilitating kinetochore assembly
title_full Long noncoding RNA SAM promotes myoblast proliferation through stabilizing Sugt1 and facilitating kinetochore assembly
title_fullStr Long noncoding RNA SAM promotes myoblast proliferation through stabilizing Sugt1 and facilitating kinetochore assembly
title_full_unstemmed Long noncoding RNA SAM promotes myoblast proliferation through stabilizing Sugt1 and facilitating kinetochore assembly
title_sort long noncoding rna sam promotes myoblast proliferation through stabilizing sugt1 and facilitating kinetochore assembly
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/fc9b05f5e91e40be8b3b91dd506c1ed7
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