Long noncoding RNA SAM promotes myoblast proliferation through stabilizing Sugt1 and facilitating kinetochore assembly

Long noncoding RNA SAM promotes myoblast proliferation through stabilizing Sugt1 and facilitating kinetochore assembly

Long noncoding RNA SAM (Sugt1 associated muscle) is upregulated in the proliferating myoblast cells. Here the authors investigate SAM knockout mice and suggest that SAM binds and stabilizes Sugt1, a co-chaperone protein that regulates kinetochore assembly.

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Detalles Bibliográficos
Autores principales: Yuying Li, Jie Yuan, Fengyuan Chen, Suyang Zhang, Yu Zhao, Xiaona Chen, Leina Lu, Liang Zhou, Ching Yan Chu, Hao Sun, Huating Wang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
Materias:
Science
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Acceso en línea:https://doaj.org/article/fc9b05f5e91e40be8b3b91dd506c1ed7
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