Detecting structural heterogeneity in single-molecule localization microscopy data

Particle fusion can improve signal-to-noise ratio in single molecule localization microscopy, but is limited by structural heterogeneity. Here, the authors demonstrate an unsupervised classification method that differentiates structurally different DNA origami structures without prior knowledge.

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Auteurs principaux: Teun A.P.M. Huijben, Hamidreza Heydarian, Alexander Auer, Florian Schueder, Ralf Jungmann, Sjoerd Stallinga, Bernd Rieger
Format: article
Langue:EN
Publié: Nature Portfolio 2021
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Accès en ligne:https://doaj.org/article/fca66482b21f4b50b38e7989abd579f0
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