Detecting structural heterogeneity in single-molecule localization microscopy data

Detecting structural heterogeneity in single-molecule localization microscopy data

Particle fusion can improve signal-to-noise ratio in single molecule localization microscopy, but is limited by structural heterogeneity. Here, the authors demonstrate an unsupervised classification method that differentiates structurally different DNA origami structures without prior knowledge.

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Autores principales: Teun A.P.M. Huijben, Hamidreza Heydarian, Alexander Auer, Florian Schueder, Ralf Jungmann, Sjoerd Stallinga, Bernd Rieger
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Science
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Acceso en línea:https://doaj.org/article/fca66482b21f4b50b38e7989abd579f0
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