Efficient Messenger RNA Delivery to the Kidney Using Renal Pelvis Injection in Mice
Renal dysfunction is often associated with the inflammatory cascade, leading to non-reversible nephrofibrosis. Gene therapy has the ability to treat the pathology. However, the difficulty in introducing genes into the kidney, via either viral vectors or plasmid DNA (pDNA), has hampered its extensive...
Saved in:
Main Authors: | Natsuko Oyama, Maho Kawaguchi, Keiji Itaka, Shigeru Kawakami |
---|---|
Format: | article |
Language: | EN |
Published: |
MDPI AG
2021
|
Subjects: | |
Online Access: | https://doaj.org/article/fcae87e9a1ee4988aeb9d5cb3859540f |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Hydrophobic Optimization of Functional Poly(TPAE-co-suberoyl chloride) for Extrahepatic mRNA Delivery following Intravenous Administration
by: Xueliang Yu, et al.
Published: (2021) -
A segment and epithelium specific messenger ribonucleic acid fragment up-regulated by estradiol in the rat oviduct
by: RIOS,MARIANA, et al.
Published: (2001) -
mRNAs expression profiles of high glucose-induced memory in human umbilical vein endothelial cells
by: Jin G, et al.
Published: (2019) -
mRNA Degradation Rates Are Coupled to Metabolic Status in <named-content content-type="genus-species">Mycobacterium smegmatis</named-content>
by: Diego A. Vargas-Blanco, et al.
Published: (2019) -
Temporal changes of Sall4 lineage contribution in developing embryos and the contribution of Sall4-lineages to postnatal germ cells in mice
by: Naoyuki Tahara, et al.
Published: (2018)