Reovirus Cell Entry Requires Functional Microtubules

ABSTRACT Mammalian reovirus binds to cell-surface glycans and junctional adhesion molecule A and enters cells by receptor-mediated endocytosis in a process dependent on β1 integrin. Within the endocytic compartment, reovirus undergoes stepwise disassembly, allowing release of the transcriptionally a...

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Bibliographic Details
Main Authors: Bernardo A. Mainou, Paula F. Zamora, Alison W. Ashbrook, Daniel C. Dorset, Kwang S. Kim, Terence S. Dermody
Format: article
Language:EN
Published: American Society for Microbiology 2013
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Online Access:https://doaj.org/article/fcb6a766d1e8481da6e91b2e6eab5671
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