Molecular mechanism underlying persistent induction of LCN2 by lipopolysaccharide in kidney fibroblasts.

The neutrophil gelatinase-associated lipocalin 2 (LCN2) is a critical inflammatory mediator persistently induced during endotoxemia, contributing to tubular damage and kidney failure. The intracellular process responsible for persistent induction of LCN2 by bacterial endotoxin Lipopolysaccharide (LP...

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Bibliographic Details
Main Authors: Trevor Glaros, Yan Fu, Jianhua Xing, Liwu Li
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2012
Subjects:
R
Q
Online Access:https://doaj.org/article/fcc0969b528841bea4b0985db5f34a61
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