Histopathologic correlation of Aspergillus endophthalmitis following uncomplicated cataract surgery

Luis J Haddock,1 Harry W Flynn Jr,1 Sander R Dubovy,1 Rahul N Khurana,2 Peter R Egbert31Department of Ophthalmology, Bascom Palmer Eye Institute, Miami Miller School of Medicine, Miami, FL, 2Northern California Retina Vitreous Associates, Mountain View, CA, 3Department of Ophthalmology, The Byers Ey...

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Autores principales:	Haddock LJ, Flynn HW Jr, Dubovy SR, Khurana RN, Egbert PR
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2012
Materias:	Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/fcc946516d704e3baab3daa1a99d8c48
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spelling	oai:doaj.org-article:fcc946516d704e3baab3daa1a99d8c482021-12-02T06:06:38ZHistopathologic correlation of Aspergillus endophthalmitis following uncomplicated cataract surgery1177-54671177-5483https://doaj.org/article/fcc946516d704e3baab3daa1a99d8c482012-09-01T00:00:00Zhttp://www.dovepress.com/histopathologic-correlation-of-aspergillus-endophthalmitis-following-u-a11099https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483Luis J Haddock,1 Harry W Flynn Jr,1 Sander R Dubovy,1 Rahul N Khurana,2 Peter R Egbert31Department of Ophthalmology, Bascom Palmer Eye Institute, Miami Miller School of Medicine, Miami, FL, 2Northern California Retina Vitreous Associates, Mountain View, CA, 3Department of Ophthalmology, The Byers Eye Institute at Stanford, Stanford University, Palo Alto, CA, USAAbstract: A clinicopathologic correlation between two patients with acute-onset Aspergillus endophthalmitis undergoing enucleation is reported. These two patients presented with pain, redness, and decreased vision following uncomplicated cataract surgery. In both patients, vitreous aspiration and intravitreal injections were the initial treatment followed later by pars plana vitrectomy for clinical worsening. Despite repeated surgical and medical interventions, the clinical course of both patients was prolonged, unsuccessful, and resulted in enucleation for a blind painful eye. Histologic examination of the enucleated specimens showed that, in spite of prolonged local and systemic therapy, there was persistent diffuse infiltration of the anterior chamber and ciliary body by a filamentous mold.Keywords: mold, enucleation, voriconazole, amphotericin BHaddock LJFlynn HW JrDubovy SRKhurana RNEgbert PRDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2012, Iss default, Pp 1573-1577 (2012)
institution	DOAJ
collection	DOAJ
language	EN
topic	Ophthalmology RE1-994
spellingShingle	Ophthalmology RE1-994 Haddock LJ Flynn HW Jr Dubovy SR Khurana RN Egbert PR Histopathologic correlation of Aspergillus endophthalmitis following uncomplicated cataract surgery
description	Luis J Haddock,1 Harry W Flynn Jr,1 Sander R Dubovy,1 Rahul N Khurana,2 Peter R Egbert31Department of Ophthalmology, Bascom Palmer Eye Institute, Miami Miller School of Medicine, Miami, FL, 2Northern California Retina Vitreous Associates, Mountain View, CA, 3Department of Ophthalmology, The Byers Eye Institute at Stanford, Stanford University, Palo Alto, CA, USAAbstract: A clinicopathologic correlation between two patients with acute-onset Aspergillus endophthalmitis undergoing enucleation is reported. These two patients presented with pain, redness, and decreased vision following uncomplicated cataract surgery. In both patients, vitreous aspiration and intravitreal injections were the initial treatment followed later by pars plana vitrectomy for clinical worsening. Despite repeated surgical and medical interventions, the clinical course of both patients was prolonged, unsuccessful, and resulted in enucleation for a blind painful eye. Histologic examination of the enucleated specimens showed that, in spite of prolonged local and systemic therapy, there was persistent diffuse infiltration of the anterior chamber and ciliary body by a filamentous mold.Keywords: mold, enucleation, voriconazole, amphotericin B
format	article
author	Haddock LJ Flynn HW Jr Dubovy SR Khurana RN Egbert PR
author_facet	Haddock LJ Flynn HW Jr Dubovy SR Khurana RN Egbert PR
author_sort	Haddock LJ
title	Histopathologic correlation of Aspergillus endophthalmitis following uncomplicated cataract surgery
title_short	Histopathologic correlation of Aspergillus endophthalmitis following uncomplicated cataract surgery
title_full	Histopathologic correlation of Aspergillus endophthalmitis following uncomplicated cataract surgery
title_fullStr	Histopathologic correlation of Aspergillus endophthalmitis following uncomplicated cataract surgery
title_full_unstemmed	Histopathologic correlation of Aspergillus endophthalmitis following uncomplicated cataract surgery
title_sort	histopathologic correlation of aspergillus endophthalmitis following uncomplicated cataract surgery
publisher	Dove Medical Press
publishDate	2012
url	https://doaj.org/article/fcc946516d704e3baab3daa1a99d8c48
work_keys_str_mv	AT haddocklj histopathologiccorrelationofaspergillusendophthalmitisfollowinguncomplicatedcataractsurgery AT flynnhwjr histopathologiccorrelationofaspergillusendophthalmitisfollowinguncomplicatedcataractsurgery AT dubovysr histopathologiccorrelationofaspergillusendophthalmitisfollowinguncomplicatedcataractsurgery AT khuranarn histopathologiccorrelationofaspergillusendophthalmitisfollowinguncomplicatedcataractsurgery AT egbertpr histopathologiccorrelationofaspergillusendophthalmitisfollowinguncomplicatedcataractsurgery
_version_	1718400089207078912

Histopathologic correlation of Aspergillus endophthalmitis following uncomplicated cataract surgery

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