Expression of the RNA helicase DDX3 and the hypoxia response in breast cancer.

Expression of the RNA helicase DDX3 and the hypoxia response in breast cancer.

<h4>Aims</h4>DDX3 is an RNA helicase that has antiapoptotic properties, and promotes proliferation and transformation. In addition, DDX3 was shown to be a direct downstream target of HIF-1α (the master regulatory of the hypoxia response) in breast cancer cell lines. However, the relation...

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Autores principales: Guus M Bol, Venu Raman, Petra van der Groep, Jeroen F Vermeulen, Arvind H Patel, Elsken van der Wall, Paul J van Diest
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/fcc986e1b2e342c79b60d68671d86112
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