Experimentally Validated Reconstruction and Analysis of a Genome-Scale Metabolic Model of an Anaerobic Neocallimastigomycota Fungus

Experimentally Validated Reconstruction and Analysis of a Genome-Scale Metabolic Model of an Anaerobic Neocallimastigomycota Fungus

ABSTRACT Anaerobic gut fungi in the phylum Neocallimastigomycota typically inhabit the digestive tracts of large mammalian herbivores, where they play an integral role in the decomposition of raw lignocellulose into its constitutive sugar monomers. However, quantitative tools to study their physiolo...

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Main Authors: St. Elmo Wilken, Jonathan M. Monk, Patrick A. Leggieri, Christopher E. Lawson, Thomas S. Lankiewicz, Susanna Seppälä, Chris G. Daum, Jerry Jenkins, Anna M. Lipzen, Stephen J. Mondo, Kerrie W. Barry, Igor V. Grigoriev, John K. Henske, Michael K. Theodorou, Bernhard O. Palsson, Linda R. Petzold, Michelle A. O’Malley
Format: article
Language:EN
Published: American Society for Microbiology 2021
Subjects:
genome-scale metabolic model
13C metabolic flux analysis
nonmodel fungus
Neocallimastigomycota
flux balance analysis
Neocallimastix lanati
Microbiology
QR1-502
Online Access:https://doaj.org/article/fccac7e8ae6141e8ab56f68f9ad37092
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https://doaj.org/article/fccac7e8ae6141e8ab56f68f9ad37092

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