A case of orbital sebaceous gland carcinoma developing in an anophthalmic socket 65 years after enucleation

Motoko Shibata,1,* Yoshihiko Usui,1,* Shunichiro Ueda,1 Hajime Matsumura,2 Toshitaka Nagao,3 Hiroshi Goto1 1Department of Ophthalmology, 2Department of Plastic and Reconstructive Surgery, 3Department of Anatomic Pathology, Tokyo Medical University, Tokyo, Japan *These authors contributed equally to...

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Autores principales:	Shibata M, Usui Y, Ueda S, Matsumura H, Nagao T, Goto H
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2013
Materias:	Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/fccfbdacd398479cb9616c6c5505230c
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spelling	oai:doaj.org-article:fccfbdacd398479cb9616c6c5505230c2021-12-02T02:55:48ZA case of orbital sebaceous gland carcinoma developing in an anophthalmic socket 65 years after enucleation1177-54671177-5483https://doaj.org/article/fccfbdacd398479cb9616c6c5505230c2013-09-01T00:00:00Zhttp://www.dovepress.com/a-case-of-orbital-sebaceous-gland-carcinoma-developing-in-an-anophthal-a14335https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483Motoko Shibata,1,* Yoshihiko Usui,1,* Shunichiro Ueda,1 Hajime Matsumura,2 Toshitaka Nagao,3 Hiroshi Goto1 1Department of Ophthalmology, 2Department of Plastic and Reconstructive Surgery, 3Department of Anatomic Pathology, Tokyo Medical University, Tokyo, Japan *These authors contributed equally to this work Abstract: Although conjunctival squamous cell carcinoma is known to develop as a result of chronic irritation from wearing an ocular prosthesis, orbital sebaceous gland carcinoma arising in an anophthalmic pocket is extremely rare. We report a 68-year-old female who developed a sebaceous gland carcinoma 65 years after her right eye was enucleated (at the age of three years) due to congenital glaucoma. The patient had noticed increasing discharge and swelling of her right eyelid. Incisional biopsies of an underlying orbital mass revealed poorly differentiated sebaceous gland carcinoma. The sebaceous gland carcinoma in this case could have been caused by chronic irritation as a result of long-standing use of a poorly fitted ocular prosthesis. The current case of a malignant tumor occurring 65 years after enucleation emphasizes the importance of long-term clinical surveillance to monitor for tumor formation. Careful examination of the anophthalmic socket should be part of the physical examination. Keywords: sebaceous gland carcinoma, anophthalmos, orbitShibata MUsui YUeda SMatsumura HNagao TGoto HDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2013, Iss default, Pp 1825-1827 (2013)
institution	DOAJ
collection	DOAJ
language	EN
topic	Ophthalmology RE1-994
spellingShingle	Ophthalmology RE1-994 Shibata M Usui Y Ueda S Matsumura H Nagao T Goto H A case of orbital sebaceous gland carcinoma developing in an anophthalmic socket 65 years after enucleation
description	Motoko Shibata,1,* Yoshihiko Usui,1,* Shunichiro Ueda,1 Hajime Matsumura,2 Toshitaka Nagao,3 Hiroshi Goto1 1Department of Ophthalmology, 2Department of Plastic and Reconstructive Surgery, 3Department of Anatomic Pathology, Tokyo Medical University, Tokyo, Japan *These authors contributed equally to this work Abstract: Although conjunctival squamous cell carcinoma is known to develop as a result of chronic irritation from wearing an ocular prosthesis, orbital sebaceous gland carcinoma arising in an anophthalmic pocket is extremely rare. We report a 68-year-old female who developed a sebaceous gland carcinoma 65 years after her right eye was enucleated (at the age of three years) due to congenital glaucoma. The patient had noticed increasing discharge and swelling of her right eyelid. Incisional biopsies of an underlying orbital mass revealed poorly differentiated sebaceous gland carcinoma. The sebaceous gland carcinoma in this case could have been caused by chronic irritation as a result of long-standing use of a poorly fitted ocular prosthesis. The current case of a malignant tumor occurring 65 years after enucleation emphasizes the importance of long-term clinical surveillance to monitor for tumor formation. Careful examination of the anophthalmic socket should be part of the physical examination. Keywords: sebaceous gland carcinoma, anophthalmos, orbit
format	article
author	Shibata M Usui Y Ueda S Matsumura H Nagao T Goto H
author_facet	Shibata M Usui Y Ueda S Matsumura H Nagao T Goto H
author_sort	Shibata M
title	A case of orbital sebaceous gland carcinoma developing in an anophthalmic socket 65 years after enucleation
title_short	A case of orbital sebaceous gland carcinoma developing in an anophthalmic socket 65 years after enucleation
title_full	A case of orbital sebaceous gland carcinoma developing in an anophthalmic socket 65 years after enucleation
title_fullStr	A case of orbital sebaceous gland carcinoma developing in an anophthalmic socket 65 years after enucleation
title_full_unstemmed	A case of orbital sebaceous gland carcinoma developing in an anophthalmic socket 65 years after enucleation
title_sort	case of orbital sebaceous gland carcinoma developing in an anophthalmic socket 65 years after enucleation
publisher	Dove Medical Press
publishDate	2013
url	https://doaj.org/article/fccfbdacd398479cb9616c6c5505230c
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A case of orbital sebaceous gland carcinoma developing in an anophthalmic socket 65 years after enucleation

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