Proteoform Analysis of Matrix Metalloproteinase-9/Gelatinase B and Discovery of Its Citrullination in Rheumatoid Arthritis Synovial Fluids

ObjectivesTo explore posttranslational modifications (PTMs), including proteolytic activation, multimerization, complex formation and citrullination of gelatinases, in particular of gelatinase B/MMP-9, and to detect in gelatin-Sepharose affinity-purified synovial fluids, the presence of specific MMP...

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Autores principales:	Bernard Grillet, Karen Yu, Estefania Ugarte-Berzal, Rik Janssens, Rafaela Vaz Sousa Pereira, Lise Boon, Erik Martens, Nele Berghmans, Isabelle Ronsse, Ilse Van Aelst, Pierre Fiten, René Conings, Jennifer Vandooren, Patrick Verschueren, Jo Van Damme, Paul Proost, Ghislain Opdenakker
Formato:	article
Lenguaje:	EN
Publicado:	Frontiers Media S.A. 2021
Materias:	matrix metalloproteinase arthritis proteoform proteolysis citrullination synovial fluid Immunologic diseases. Allergy RC581-607
Acceso en línea:	https://doaj.org/article/fcdb7e2221a94516bc4d928080b5e8a7
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Proteoform Analysis of Matrix Metalloproteinase-9/Gelatinase B and Discovery of Its Citrullination in Rheumatoid Arthritis Synovial Fluids

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