Abandoned acid? Understanding adherence to bisphosphonate medications for the prevention of osteoporosis among older women: a qualitative longitudinal study.

<h4>Background</h4>There is significant morbidity and mortality caused by the complications of osteoporosis, for which ageing is the greatest epidemiological risk factor. Preventive medications to delay osteoporosis are available, but little is known about motivators to adhere to these i...

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Autores principales:	Charlotte Salter, Lisa McDaid, Debi Bhattacharya, Richard Holland, Tarnya Marshall, Amanda Howe
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2014
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/fcdddbc7cb6e4aa19960332ba8566318
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spelling	oai:doaj.org-article:fcdddbc7cb6e4aa19960332ba85663182021-11-18T08:39:10ZAbandoned acid? Understanding adherence to bisphosphonate medications for the prevention of osteoporosis among older women: a qualitative longitudinal study.1932-620310.1371/journal.pone.0083552https://doaj.org/article/fcdddbc7cb6e4aa19960332ba85663182014-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24392086/?tool=EBIhttps://doaj.org/toc/1932-6203<h4>Background</h4>There is significant morbidity and mortality caused by the complications of osteoporosis, for which ageing is the greatest epidemiological risk factor. Preventive medications to delay osteoporosis are available, but little is known about motivators to adhere to these in the context of a symptomless condition with evidence based on screening results.<h4>Aim</h4>To describe key perceptions that influence older women's adherence and persistence with prescribed medication when identified to be at a higher than average risk of fracture.<h4>Design of study</h4>A longitudinal qualitative study embedded within a multi-centre trial exploring the effectiveness of screening for prevention of fractures.<h4>Setting</h4>Primary care, Norfolk. United Kingdom.<h4>Methods</h4>Thirty older women aged 70-85 years of age who were offered preventive medication for osteoporosis and agreed to undertake two interviews at 6 and 24 months post-first prescription.<h4>Results</h4>There were no overall predictors of adherence which varied markedly over time. Participants' perceptions and motivations to persist with medication were influenced by six core themes: understanding adherence and non-adherence, motivations and self-care, appraising and prioritising risk, anticipating and managing side effects, problems of understanding, and decision making around medication. Those engaged with supportive professionals could better tolerate and overcome barriers such as side-effects.<h4>Conclusions</h4>Many issues are raised following screening in a cohort of women who have not previously sought advice about their bone health. Adherence to preventive medication for osteoporosis is complex and multifaceted. Individual participant understanding, choice, risk and perceived need all interact to produce unpredictable patterns of usage and acceptability. There are clear implications for practice and health professionals should not assume adherence in any older women prescribed medication for the prevention of osteoporosis. The beliefs and motivations of participants and their healthcare providers regarding the need to establish acceptable medication regimes is key to promoting and sustaining adherence.Charlotte SalterLisa McDaidDebi BhattacharyaRichard HollandTarnya MarshallAmanda HowePublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 9, Iss 1, p e83552 (2014)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Charlotte Salter Lisa McDaid Debi Bhattacharya Richard Holland Tarnya Marshall Amanda Howe Abandoned acid? Understanding adherence to bisphosphonate medications for the prevention of osteoporosis among older women: a qualitative longitudinal study.
description	<h4>Background</h4>There is significant morbidity and mortality caused by the complications of osteoporosis, for which ageing is the greatest epidemiological risk factor. Preventive medications to delay osteoporosis are available, but little is known about motivators to adhere to these in the context of a symptomless condition with evidence based on screening results.<h4>Aim</h4>To describe key perceptions that influence older women's adherence and persistence with prescribed medication when identified to be at a higher than average risk of fracture.<h4>Design of study</h4>A longitudinal qualitative study embedded within a multi-centre trial exploring the effectiveness of screening for prevention of fractures.<h4>Setting</h4>Primary care, Norfolk. United Kingdom.<h4>Methods</h4>Thirty older women aged 70-85 years of age who were offered preventive medication for osteoporosis and agreed to undertake two interviews at 6 and 24 months post-first prescription.<h4>Results</h4>There were no overall predictors of adherence which varied markedly over time. Participants' perceptions and motivations to persist with medication were influenced by six core themes: understanding adherence and non-adherence, motivations and self-care, appraising and prioritising risk, anticipating and managing side effects, problems of understanding, and decision making around medication. Those engaged with supportive professionals could better tolerate and overcome barriers such as side-effects.<h4>Conclusions</h4>Many issues are raised following screening in a cohort of women who have not previously sought advice about their bone health. Adherence to preventive medication for osteoporosis is complex and multifaceted. Individual participant understanding, choice, risk and perceived need all interact to produce unpredictable patterns of usage and acceptability. There are clear implications for practice and health professionals should not assume adherence in any older women prescribed medication for the prevention of osteoporosis. The beliefs and motivations of participants and their healthcare providers regarding the need to establish acceptable medication regimes is key to promoting and sustaining adherence.
format	article
author	Charlotte Salter Lisa McDaid Debi Bhattacharya Richard Holland Tarnya Marshall Amanda Howe
author_facet	Charlotte Salter Lisa McDaid Debi Bhattacharya Richard Holland Tarnya Marshall Amanda Howe
author_sort	Charlotte Salter
title	Abandoned acid? Understanding adherence to bisphosphonate medications for the prevention of osteoporosis among older women: a qualitative longitudinal study.
title_short	Abandoned acid? Understanding adherence to bisphosphonate medications for the prevention of osteoporosis among older women: a qualitative longitudinal study.
title_full	Abandoned acid? Understanding adherence to bisphosphonate medications for the prevention of osteoporosis among older women: a qualitative longitudinal study.
title_fullStr	Abandoned acid? Understanding adherence to bisphosphonate medications for the prevention of osteoporosis among older women: a qualitative longitudinal study.
title_full_unstemmed	Abandoned acid? Understanding adherence to bisphosphonate medications for the prevention of osteoporosis among older women: a qualitative longitudinal study.
title_sort	abandoned acid? understanding adherence to bisphosphonate medications for the prevention of osteoporosis among older women: a qualitative longitudinal study.
publisher	Public Library of Science (PLoS)
publishDate	2014
url	https://doaj.org/article/fcdddbc7cb6e4aa19960332ba8566318
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Abandoned acid? Understanding adherence to bisphosphonate medications for the prevention of osteoporosis among older women: a qualitative longitudinal study.

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