Efficient viral delivery of Cas9 into human safe harbor
Abstract Gene editing using CRISPR/Cas9 is a promising method to cure many human genetic diseases. We have developed an efficient system to deliver Cas9 into the adeno-associated virus integration site 1 (AAVS1) locus, known as a safe harbor, using lentivirus and AAV viral vectors, as a step toward...
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Autores principales: | Hideki Hayashi, Yoshinao Kubo, Mai Izumida, Toshifumi Matsuyama |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2020
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Materias: | |
Acceso en línea: | https://doaj.org/article/fce61c5bca0b424ab95f614d32a7cd92 |
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