Relationships between monocyte count to high-density lipoprotein cholesterol ratio and cardiovascular outcomes in patients commencing dialysis

Objective High monocyte to high-density lipoprotein cholesterol ratio (MHR) is known to be a risk factor for cardiovascular (CV) complications. We aimed to evaluate the relationship between MHR and CV outcomes in patients commencing dialysis. Methods The medical records of patients who started maint...

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Autores principales:	Dongryul Kim, Da Won Kim, Yeon Hee Lee, So Yeon Park, Young Woo Song, Hyeonoh Shin, Hye Eun Yoon, Hoon Suk Park, Bum Soon Choi, Byung Soo Kim, Tae Hyun Ban, Seok Joon Shin
Formato:	article
Lenguaje:	EN
Publicado:	SAGE Publishing 2021
Materias:	Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/fce8a33b0644476fb8b2213f97c0fca1
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spelling	oai:doaj.org-article:fce8a33b0644476fb8b2213f97c0fca12021-11-19T01:33:19ZRelationships between monocyte count to high-density lipoprotein cholesterol ratio and cardiovascular outcomes in patients commencing dialysis1473-230010.1177/03000605211058861https://doaj.org/article/fce8a33b0644476fb8b2213f97c0fca12021-11-01T00:00:00Zhttps://doi.org/10.1177/03000605211058861https://doaj.org/toc/1473-2300Objective High monocyte to high-density lipoprotein cholesterol ratio (MHR) is known to be a risk factor for cardiovascular (CV) complications. We aimed to evaluate the relationship between MHR and CV outcomes in patients commencing dialysis. Methods The medical records of patients who started maintenance dialysis between January 2006 and July 2017 were reviewed. The primary outcomes were all-cause mortality and overall CV mortality and the secondary outcomes were CV event-free survival and the incidence of CV complications. Results Five hundred ninety-seven patients were enrolled and allocated to low- or high-MHR groups. All-cause mortality did not differ between the groups during a mean follow-up period of 3.9 years. In addition, overall CV mortality did not differ between the groups. However, CV event-free survival was significantly lower in the high-MHR group than in the low-MHR group (47.5% vs . 59.0%). Multivariate Cox regression analysis showed that high MHR was an independent predictor of CV events (HR 1.886, 95% CI 1.015–3.505). Conclusion High MHR at the time of initiation of dialysis may represent a useful predictor of CV complications.Dongryul KimDa Won KimYeon Hee LeeSo Yeon ParkYoung Woo SongHyeonoh ShinHye Eun YoonHoon Suk ParkBum Soon ChoiByung Soo KimTae Hyun BanSeok Joon ShinSAGE PublishingarticleMedicine (General)R5-920ENJournal of International Medical Research, Vol 49 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine (General) R5-920
spellingShingle	Medicine (General) R5-920 Dongryul Kim Da Won Kim Yeon Hee Lee So Yeon Park Young Woo Song Hyeonoh Shin Hye Eun Yoon Hoon Suk Park Bum Soon Choi Byung Soo Kim Tae Hyun Ban Seok Joon Shin Relationships between monocyte count to high-density lipoprotein cholesterol ratio and cardiovascular outcomes in patients commencing dialysis
description	Objective High monocyte to high-density lipoprotein cholesterol ratio (MHR) is known to be a risk factor for cardiovascular (CV) complications. We aimed to evaluate the relationship between MHR and CV outcomes in patients commencing dialysis. Methods The medical records of patients who started maintenance dialysis between January 2006 and July 2017 were reviewed. The primary outcomes were all-cause mortality and overall CV mortality and the secondary outcomes were CV event-free survival and the incidence of CV complications. Results Five hundred ninety-seven patients were enrolled and allocated to low- or high-MHR groups. All-cause mortality did not differ between the groups during a mean follow-up period of 3.9 years. In addition, overall CV mortality did not differ between the groups. However, CV event-free survival was significantly lower in the high-MHR group than in the low-MHR group (47.5% vs . 59.0%). Multivariate Cox regression analysis showed that high MHR was an independent predictor of CV events (HR 1.886, 95% CI 1.015–3.505). Conclusion High MHR at the time of initiation of dialysis may represent a useful predictor of CV complications.
format	article
author	Dongryul Kim Da Won Kim Yeon Hee Lee So Yeon Park Young Woo Song Hyeonoh Shin Hye Eun Yoon Hoon Suk Park Bum Soon Choi Byung Soo Kim Tae Hyun Ban Seok Joon Shin
author_facet	Dongryul Kim Da Won Kim Yeon Hee Lee So Yeon Park Young Woo Song Hyeonoh Shin Hye Eun Yoon Hoon Suk Park Bum Soon Choi Byung Soo Kim Tae Hyun Ban Seok Joon Shin
author_sort	Dongryul Kim
title	Relationships between monocyte count to high-density lipoprotein cholesterol ratio and cardiovascular outcomes in patients commencing dialysis
title_short	Relationships between monocyte count to high-density lipoprotein cholesterol ratio and cardiovascular outcomes in patients commencing dialysis
title_full	Relationships between monocyte count to high-density lipoprotein cholesterol ratio and cardiovascular outcomes in patients commencing dialysis
title_fullStr	Relationships between monocyte count to high-density lipoprotein cholesterol ratio and cardiovascular outcomes in patients commencing dialysis
title_full_unstemmed	Relationships between monocyte count to high-density lipoprotein cholesterol ratio and cardiovascular outcomes in patients commencing dialysis
title_sort	relationships between monocyte count to high-density lipoprotein cholesterol ratio and cardiovascular outcomes in patients commencing dialysis
publisher	SAGE Publishing
publishDate	2021
url	https://doaj.org/article/fce8a33b0644476fb8b2213f97c0fca1
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Relationships between monocyte count to high-density lipoprotein cholesterol ratio and cardiovascular outcomes in patients commencing dialysis

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