Nodular basal cell carcinoma of the face successfully treated with ingenol mebutate 0.015% gel

Surgical excision is the first-choice treatment for basal cell carcinoma (BCC). Other treatments with topical agents such as 5-fluoruracil or imiquimod have also been suggested for use in superficial BCC (sBCC). Ingenol mebutate (IM) is a novel agent employed in the treatment of superficial actinic...

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Autores principales:	Silvia S. Iannazzone, Vito Ingordo
Formato:	article
Lenguaje:	EN
Publicado:	Mattioli1885 2018
Materias:	ingenol mebutate basal cell carcinoma nodular basal cell carcinoma Dermatology RL1-803
Acceso en línea:	https://doaj.org/article/fd0850f3fbb94610801cd8d07e34fc84
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spelling	oai:doaj.org-article:fd0850f3fbb94610801cd8d07e34fc842021-11-17T08:30:15ZNodular basal cell carcinoma of the face successfully treated with ingenol mebutate 0.015% gel2160-9381https://doaj.org/article/fd0850f3fbb94610801cd8d07e34fc842018-04-01T00:00:00Zhttp://dpcj.org/index.php/dpc/article/view/411https://doaj.org/toc/2160-9381 Surgical excision is the first-choice treatment for basal cell carcinoma (BCC). Other treatments with topical agents such as 5-fluoruracil or imiquimod have also been suggested for use in superficial BCC (sBCC). Ingenol mebutate (IM) is a novel agent employed in the treatment of superficial actinic keratoses. The drug has been also successfully used in the treatment of sBCC. A case of large nodular BCC (nBCC) of the face in a 100-year-old inoperable woman is described. IM 0.015% gel was applied once daily for three consecutive days. This dose regimen was repeated for seven rounds within 11 months, with complete cure of the tumor. Mild local skin reactions, which were tolerated well, were observed. Selected cases of nBCC could be treated with IM gel, but the optimal concentration of the drug and the standard dose regimen of treatment are yet to be determined. Silvia S. IannazzoneVito IngordoMattioli1885articleingenol mebutatebasal cell carcinomanodular basal cell carcinomaDermatologyRL1-803ENDermatology Practical & Conceptual, Vol 8, Iss 1 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	ingenol mebutate basal cell carcinoma nodular basal cell carcinoma Dermatology RL1-803
spellingShingle	ingenol mebutate basal cell carcinoma nodular basal cell carcinoma Dermatology RL1-803 Silvia S. Iannazzone Vito Ingordo Nodular basal cell carcinoma of the face successfully treated with ingenol mebutate 0.015% gel
description	Surgical excision is the first-choice treatment for basal cell carcinoma (BCC). Other treatments with topical agents such as 5-fluoruracil or imiquimod have also been suggested for use in superficial BCC (sBCC). Ingenol mebutate (IM) is a novel agent employed in the treatment of superficial actinic keratoses. The drug has been also successfully used in the treatment of sBCC. A case of large nodular BCC (nBCC) of the face in a 100-year-old inoperable woman is described. IM 0.015% gel was applied once daily for three consecutive days. This dose regimen was repeated for seven rounds within 11 months, with complete cure of the tumor. Mild local skin reactions, which were tolerated well, were observed. Selected cases of nBCC could be treated with IM gel, but the optimal concentration of the drug and the standard dose regimen of treatment are yet to be determined.
format	article
author	Silvia S. Iannazzone Vito Ingordo
author_facet	Silvia S. Iannazzone Vito Ingordo
author_sort	Silvia S. Iannazzone
title	Nodular basal cell carcinoma of the face successfully treated with ingenol mebutate 0.015% gel
title_short	Nodular basal cell carcinoma of the face successfully treated with ingenol mebutate 0.015% gel
title_full	Nodular basal cell carcinoma of the face successfully treated with ingenol mebutate 0.015% gel
title_fullStr	Nodular basal cell carcinoma of the face successfully treated with ingenol mebutate 0.015% gel
title_full_unstemmed	Nodular basal cell carcinoma of the face successfully treated with ingenol mebutate 0.015% gel
title_sort	nodular basal cell carcinoma of the face successfully treated with ingenol mebutate 0.015% gel
publisher	Mattioli1885
publishDate	2018
url	https://doaj.org/article/fd0850f3fbb94610801cd8d07e34fc84
work_keys_str_mv	AT silviasiannazzone nodularbasalcellcarcinomaofthefacesuccessfullytreatedwithingenolmebutate0015gel AT vitoingordo nodularbasalcellcarcinomaofthefacesuccessfullytreatedwithingenolmebutate0015gel
_version_	1718425776733290496

Nodular basal cell carcinoma of the face successfully treated with ingenol mebutate 0.015% gel

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