Feedback within the inter-cellular communication and tumorigenesis in carcinomas.

The classical somatic mutation theory (SMT) of carcinogenesis and metastasis postulates that malignant transformation occurs in cells that accumulate a sufficient amount of mutations in the appropriate oncogenes and/or tumor suppressor genes. These mutations result in cell-autonomous activation of t...

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Autores principales: Felix Rückert, Robert Grützmann, Christian Pilarsky
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
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Acceso en línea:https://doaj.org/article/fd12fab9d40c4ffa82e096110de5f0f4
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