Feedback within the inter-cellular communication and tumorigenesis in carcinomas.
The classical somatic mutation theory (SMT) of carcinogenesis and metastasis postulates that malignant transformation occurs in cells that accumulate a sufficient amount of mutations in the appropriate oncogenes and/or tumor suppressor genes. These mutations result in cell-autonomous activation of t...
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Autores principales: | Felix Rückert, Robert Grützmann, Christian Pilarsky |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2012
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Materias: | |
Acceso en línea: | https://doaj.org/article/fd12fab9d40c4ffa82e096110de5f0f4 |
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