A DNA packaging motor inchworms along one strand allowing it to adapt to alternative double-helical structures

Ring ATPase translocases that operate on disordered substrates adopt lockwasher architectures and use a hand-over-hand mechanism. By challenging the dsDNA packaging motor of bacteriophage ϕ29 with hybrid and dsRNA, the authors propose that the motor cycles between planar and lock-washer structures.

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Autores principales:	Juan P. Castillo, Alexander B. Tong, Sara Tafoya, Paul J. Jardine, Carlos Bustamante
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/fd2702eb7c8e4254a416e2dbc6cb6580
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spelling	oai:doaj.org-article:fd2702eb7c8e4254a416e2dbc6cb65802021-12-02T14:58:23ZA DNA packaging motor inchworms along one strand allowing it to adapt to alternative double-helical structures10.1038/s41467-021-23725-52041-1723https://doaj.org/article/fd2702eb7c8e4254a416e2dbc6cb65802021-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-23725-5https://doaj.org/toc/2041-1723Ring ATPase translocases that operate on disordered substrates adopt lockwasher architectures and use a hand-over-hand mechanism. By challenging the dsDNA packaging motor of bacteriophage ϕ29 with hybrid and dsRNA, the authors propose that the motor cycles between planar and lock-washer structures.Juan P. CastilloAlexander B. TongSara TafoyaPaul J. JardineCarlos BustamanteNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-8 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Juan P. Castillo Alexander B. Tong Sara Tafoya Paul J. Jardine Carlos Bustamante A DNA packaging motor inchworms along one strand allowing it to adapt to alternative double-helical structures
description	Ring ATPase translocases that operate on disordered substrates adopt lockwasher architectures and use a hand-over-hand mechanism. By challenging the dsDNA packaging motor of bacteriophage ϕ29 with hybrid and dsRNA, the authors propose that the motor cycles between planar and lock-washer structures.
format	article
author	Juan P. Castillo Alexander B. Tong Sara Tafoya Paul J. Jardine Carlos Bustamante
author_facet	Juan P. Castillo Alexander B. Tong Sara Tafoya Paul J. Jardine Carlos Bustamante
author_sort	Juan P. Castillo
title	A DNA packaging motor inchworms along one strand allowing it to adapt to alternative double-helical structures
title_short	A DNA packaging motor inchworms along one strand allowing it to adapt to alternative double-helical structures
title_full	A DNA packaging motor inchworms along one strand allowing it to adapt to alternative double-helical structures
title_fullStr	A DNA packaging motor inchworms along one strand allowing it to adapt to alternative double-helical structures
title_full_unstemmed	A DNA packaging motor inchworms along one strand allowing it to adapt to alternative double-helical structures
title_sort	dna packaging motor inchworms along one strand allowing it to adapt to alternative double-helical structures
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/fd2702eb7c8e4254a416e2dbc6cb6580
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A DNA packaging motor inchworms along one strand allowing it to adapt to alternative double-helical structures

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