A conserved influenza A virus nucleoprotein code controls specific viral genome packaging

The nucleotide sequence of the eight genomic RNA segments of influenza A virus provides essential packaging signals, but how these sequences are recognized is unknown. Here, Moreira et al. identify conserved amino acids in the viral nucleoprotein that regulate packaging of RNA segments.

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Autores principales: Étori Aguiar Moreira, Anna Weber, Hardin Bolte, Larissa Kolesnikova, Sebastian Giese, Seema Lakdawala, Martin Beer, Gert Zimmer, Adolfo García-Sastre, Martin Schwemmle, Mindaugas Juozapaitis
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Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/fd2af3891b1d4a18955cefaa09570b16
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spelling oai:doaj.org-article:fd2af3891b1d4a18955cefaa09570b162021-12-02T15:34:56ZA conserved influenza A virus nucleoprotein code controls specific viral genome packaging10.1038/ncomms128612041-1723https://doaj.org/article/fd2af3891b1d4a18955cefaa09570b162016-09-01T00:00:00Zhttps://doi.org/10.1038/ncomms12861https://doaj.org/toc/2041-1723The nucleotide sequence of the eight genomic RNA segments of influenza A virus provides essential packaging signals, but how these sequences are recognized is unknown. Here, Moreira et al. identify conserved amino acids in the viral nucleoprotein that regulate packaging of RNA segments.Étori Aguiar MoreiraAnna WeberHardin BolteLarissa KolesnikovaSebastian GieseSeema LakdawalaMartin BeerGert ZimmerAdolfo García-SastreMartin SchwemmleMindaugas JuozapaitisNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Étori Aguiar Moreira
Anna Weber
Hardin Bolte
Larissa Kolesnikova
Sebastian Giese
Seema Lakdawala
Martin Beer
Gert Zimmer
Adolfo García-Sastre
Martin Schwemmle
Mindaugas Juozapaitis
A conserved influenza A virus nucleoprotein code controls specific viral genome packaging
description The nucleotide sequence of the eight genomic RNA segments of influenza A virus provides essential packaging signals, but how these sequences are recognized is unknown. Here, Moreira et al. identify conserved amino acids in the viral nucleoprotein that regulate packaging of RNA segments.
format article
author Étori Aguiar Moreira
Anna Weber
Hardin Bolte
Larissa Kolesnikova
Sebastian Giese
Seema Lakdawala
Martin Beer
Gert Zimmer
Adolfo García-Sastre
Martin Schwemmle
Mindaugas Juozapaitis
author_facet Étori Aguiar Moreira
Anna Weber
Hardin Bolte
Larissa Kolesnikova
Sebastian Giese
Seema Lakdawala
Martin Beer
Gert Zimmer
Adolfo García-Sastre
Martin Schwemmle
Mindaugas Juozapaitis
author_sort Étori Aguiar Moreira
title A conserved influenza A virus nucleoprotein code controls specific viral genome packaging
title_short A conserved influenza A virus nucleoprotein code controls specific viral genome packaging
title_full A conserved influenza A virus nucleoprotein code controls specific viral genome packaging
title_fullStr A conserved influenza A virus nucleoprotein code controls specific viral genome packaging
title_full_unstemmed A conserved influenza A virus nucleoprotein code controls specific viral genome packaging
title_sort conserved influenza a virus nucleoprotein code controls specific viral genome packaging
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/fd2af3891b1d4a18955cefaa09570b16
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