Type I Interferon Promotes Antitumor T Cell Response in CRPC by Regulating MDSC

Type I Interferon Promotes Antitumor T Cell Response in CRPC by Regulating MDSC

Background: Metastatic castration-resistant prostate cancer (CRPC) is the leading cause of death among prostate cancer patients. Here, our aim was to ascertain the immune regulatory mechanisms involved in CRPC development and identify potential immunotherapies against CRPC. Methods: A CRPC model was...

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Autores principales: Lilv Fan, Guiliang Xu, Jingjing Cao, Min Li, Huihui Zhang, Fanlin Li, Xinyue Qi, Xiaoqing Zhang, Zeyu Li, Ping Han, Xuanming Yang
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
Materias:
IFNα
prostate cancer
G-MDSC
immunotherapy
Neoplasms. Tumors. Oncology. Including cancer and carcinogens
RC254-282
Acceso en línea:https://doaj.org/article/fd436a2d1e8b4d2a9fc27ac955ff189d
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