Risk factors and mortality in patients with pneumonia and elevated troponin levels

Abstract Pneumonia in hospitalized patients is associated with myocardial injury. In this study, we evaluated risk factors for myocardial injury in hospitalized patients with pneumonia and its prognostic value. We retrieved all patients who were hospitalized in internal medicine departments in a ter...

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Autores principales:	Orly Efros, Shelly Soffer, Avshalom Leibowitz, Alexander Fardman, Robert Klempfner, Eshcar Meisel, Ehud Grossman
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/fd44c289252c45efac6395a7cd8a973a
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spelling	oai:doaj.org-article:fd44c289252c45efac6395a7cd8a973a2021-12-02T15:11:50ZRisk factors and mortality in patients with pneumonia and elevated troponin levels10.1038/s41598-020-78287-12045-2322https://doaj.org/article/fd44c289252c45efac6395a7cd8a973a2020-12-01T00:00:00Zhttps://doi.org/10.1038/s41598-020-78287-1https://doaj.org/toc/2045-2322Abstract Pneumonia in hospitalized patients is associated with myocardial injury. In this study, we evaluated risk factors for myocardial injury in hospitalized patients with pneumonia and its prognostic value. We retrieved all patients who were hospitalized in internal medicine departments in a tertiary medical center between 2008 and 2019 with a diagnosis of pneumonia. From 2008 to 2019 a total of 20,683 adult patients were hospitalized in internal medicine wards in the Sheba Medical Center with a diagnosis of pneumonia, 8195 were tested for troponin levels, and 3207 had elevated levels. Risk factors for elevated troponin levels were age, prior diagnosis of ischemic heart disease, and elevated creatinine level upon admission. The in-hospital mortality and 1-year mortality rate were higher among patients who had elevated troponin levels when using a propensity score-based matched analysis. In conclusion, in hospitalized patients with pneumonia elevated troponin levels have a major impact on prognosis. Hence, troponin levels may be used as another tool of risk stratification for patients hospitalized with pneumonia.Orly EfrosShelly SofferAvshalom LeibowitzAlexander FardmanRobert KlempfnerEshcar MeiselEhud GrossmanNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 10, Iss 1, Pp 1-7 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Orly Efros Shelly Soffer Avshalom Leibowitz Alexander Fardman Robert Klempfner Eshcar Meisel Ehud Grossman Risk factors and mortality in patients with pneumonia and elevated troponin levels
description	Abstract Pneumonia in hospitalized patients is associated with myocardial injury. In this study, we evaluated risk factors for myocardial injury in hospitalized patients with pneumonia and its prognostic value. We retrieved all patients who were hospitalized in internal medicine departments in a tertiary medical center between 2008 and 2019 with a diagnosis of pneumonia. From 2008 to 2019 a total of 20,683 adult patients were hospitalized in internal medicine wards in the Sheba Medical Center with a diagnosis of pneumonia, 8195 were tested for troponin levels, and 3207 had elevated levels. Risk factors for elevated troponin levels were age, prior diagnosis of ischemic heart disease, and elevated creatinine level upon admission. The in-hospital mortality and 1-year mortality rate were higher among patients who had elevated troponin levels when using a propensity score-based matched analysis. In conclusion, in hospitalized patients with pneumonia elevated troponin levels have a major impact on prognosis. Hence, troponin levels may be used as another tool of risk stratification for patients hospitalized with pneumonia.
format	article
author	Orly Efros Shelly Soffer Avshalom Leibowitz Alexander Fardman Robert Klempfner Eshcar Meisel Ehud Grossman
author_facet	Orly Efros Shelly Soffer Avshalom Leibowitz Alexander Fardman Robert Klempfner Eshcar Meisel Ehud Grossman
author_sort	Orly Efros
title	Risk factors and mortality in patients with pneumonia and elevated troponin levels
title_short	Risk factors and mortality in patients with pneumonia and elevated troponin levels
title_full	Risk factors and mortality in patients with pneumonia and elevated troponin levels
title_fullStr	Risk factors and mortality in patients with pneumonia and elevated troponin levels
title_full_unstemmed	Risk factors and mortality in patients with pneumonia and elevated troponin levels
title_sort	risk factors and mortality in patients with pneumonia and elevated troponin levels
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/fd44c289252c45efac6395a7cd8a973a
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Risk factors and mortality in patients with pneumonia and elevated troponin levels

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