Assessment of established techniques to determine developmental and malignant potential of human pluripotent stem cells
The International Stem Cell Initiative tests methods in a multisite study to detect pluripotency and teratoma formation (PluriTest, Embryoid Body and Teratoma methods) in human pluripotent stem cells. Here, the authors provide guidelines for their application: only the teratoma assay offers evidence...
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Nature Portfolio
2018
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oai:doaj.org-article:fd4828bc605d4930a3f4f704f5ee78762021-12-02T17:32:34ZAssessment of established techniques to determine developmental and malignant potential of human pluripotent stem cells10.1038/s41467-018-04011-32041-1723https://doaj.org/article/fd4828bc605d4930a3f4f704f5ee78762018-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-04011-3https://doaj.org/toc/2041-1723The International Stem Cell Initiative tests methods in a multisite study to detect pluripotency and teratoma formation (PluriTest, Embryoid Body and Teratoma methods) in human pluripotent stem cells. Here, the authors provide guidelines for their application: only the teratoma assay offers evidence of malignant potential.The International Stem Cell InitiativeNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-15 (2018) |
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Science Q The International Stem Cell Initiative Assessment of established techniques to determine developmental and malignant potential of human pluripotent stem cells |
description |
The International Stem Cell Initiative tests methods in a multisite study to detect pluripotency and teratoma formation (PluriTest, Embryoid Body and Teratoma methods) in human pluripotent stem cells. Here, the authors provide guidelines for their application: only the teratoma assay offers evidence of malignant potential. |
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article |
author |
The International Stem Cell Initiative |
author_facet |
The International Stem Cell Initiative |
author_sort |
The International Stem Cell Initiative |
title |
Assessment of established techniques to determine developmental and malignant potential of human pluripotent stem cells |
title_short |
Assessment of established techniques to determine developmental and malignant potential of human pluripotent stem cells |
title_full |
Assessment of established techniques to determine developmental and malignant potential of human pluripotent stem cells |
title_fullStr |
Assessment of established techniques to determine developmental and malignant potential of human pluripotent stem cells |
title_full_unstemmed |
Assessment of established techniques to determine developmental and malignant potential of human pluripotent stem cells |
title_sort |
assessment of established techniques to determine developmental and malignant potential of human pluripotent stem cells |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/fd4828bc605d4930a3f4f704f5ee7876 |
work_keys_str_mv |
AT theinternationalstemcellinitiative assessmentofestablishedtechniquestodeterminedevelopmentalandmalignantpotentialofhumanpluripotentstemcells |
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1718380285100294144 |