Assessment of established techniques to determine developmental and malignant potential of human pluripotent stem cells

The International Stem Cell Initiative tests methods in a multisite study to detect pluripotency and teratoma formation (PluriTest, Embryoid Body and Teratoma methods) in human pluripotent stem cells. Here, the authors provide guidelines for their application: only the teratoma assay offers evidence...

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Main Author:	The International Stem Cell Initiative
Format:	article
Language:	EN
Published:	Nature Portfolio 2018
Subjects:	Science Q
Online Access:	https://doaj.org/article/fd4828bc605d4930a3f4f704f5ee7876
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spelling	oai:doaj.org-article:fd4828bc605d4930a3f4f704f5ee78762021-12-02T17:32:34ZAssessment of established techniques to determine developmental and malignant potential of human pluripotent stem cells10.1038/s41467-018-04011-32041-1723https://doaj.org/article/fd4828bc605d4930a3f4f704f5ee78762018-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-04011-3https://doaj.org/toc/2041-1723The International Stem Cell Initiative tests methods in a multisite study to detect pluripotency and teratoma formation (PluriTest, Embryoid Body and Teratoma methods) in human pluripotent stem cells. Here, the authors provide guidelines for their application: only the teratoma assay offers evidence of malignant potential.The International Stem Cell InitiativeNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q The International Stem Cell Initiative Assessment of established techniques to determine developmental and malignant potential of human pluripotent stem cells
description	The International Stem Cell Initiative tests methods in a multisite study to detect pluripotency and teratoma formation (PluriTest, Embryoid Body and Teratoma methods) in human pluripotent stem cells. Here, the authors provide guidelines for their application: only the teratoma assay offers evidence of malignant potential.
format	article
author	The International Stem Cell Initiative
author_facet	The International Stem Cell Initiative
author_sort	The International Stem Cell Initiative
title	Assessment of established techniques to determine developmental and malignant potential of human pluripotent stem cells
title_short	Assessment of established techniques to determine developmental and malignant potential of human pluripotent stem cells
title_full	Assessment of established techniques to determine developmental and malignant potential of human pluripotent stem cells
title_fullStr	Assessment of established techniques to determine developmental and malignant potential of human pluripotent stem cells
title_full_unstemmed	Assessment of established techniques to determine developmental and malignant potential of human pluripotent stem cells
title_sort	assessment of established techniques to determine developmental and malignant potential of human pluripotent stem cells
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/fd4828bc605d4930a3f4f704f5ee7876
work_keys_str_mv	AT theinternationalstemcellinitiative assessmentofestablishedtechniquestodeterminedevelopmentalandmalignantpotentialofhumanpluripotentstemcells
_version_	1718380285100294144

Assessment of established techniques to determine developmental and malignant potential of human pluripotent stem cells

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