Biomimetic artificial organelles with in vitro and in vivo activity triggered by reduction in microenvironment

Biomimetic artificial organelles with in vitro and in vivo activity triggered by reduction in microenvironment

The efficacy of stimuli-responsive enzyme delivery systems is usually limited to in vitro applications. Here the authors form artificial organelles by inserting stimuli-responsive protein gates in membranes of polymersomes loaded with enzymes and obtain a triggered functionality both in vitro and in...

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Autores principales: T. Einfalt, D. Witzigmann, C. Edlinger, S. Sieber, R. Goers, A. Najer, M. Spulber, O. Onaca-Fischer, J. Huwyler, C. G. Palivan
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Science
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Acceso en línea:https://doaj.org/article/fd48b4028b1543f0b1df3998fb2b1d1c
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