DUSP5 expression in left ventricular cardiomyocytes of young hearts regulates thyroid hormone (T3)-induced proliferative ERK1/2 signaling

DUSP5 expression in left ventricular cardiomyocytes of young hearts regulates thyroid hormone (T3)-induced proliferative ERK1/2 signaling

Abstract Cardiomyocytes of newborn mice proliferate after injury or exposure to growth factors. However, these responses are diminished after postnatal day-6 (P6), representing a barrier to building new cardiac muscle in adults. We have previously shown that exogenous thyroid hormone (T3) stimulates...

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Autores principales: Nikolay Bogush, Lin Tan, Hussain Naib, Ebrahim Faizullabhoy, John W. Calvert, Siiri E. Iismaa, Ankan Gupta, Ramani Ramchandran, David I. K. Martin, Robert M. Graham, Ahsan Husain, Nawazish Naqvi
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/fd5f777a271c4c42af5f2172602fd2f5
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