A Novel Mutation of the KLK6 Gene in a Family With Knee Osteoarthritis

To investigate the correlation between gene mutation and knee osteoarthritis (KOA), a whole-exome sequencing (WES) was applied to analyze blood samples of four KOA patients and two normal subjects in a family. Gene mutations were identified by gene-trapping and high-throughput sequencing analysis ac...

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Autores principales: Yanzhi Ge, Chenfen Zhou, Xiujuan Xiao, Zhijiang Jin, Li Zhou, Zuxiang Chen, Fucun Liu, Qiang Yuan, Guoqing Zhang, Letian Shan, Peijian Tong
Formato: article
Lenguaje:EN
Publicado: Frontiers Media S.A. 2021
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Acceso en línea:https://doaj.org/article/fd63f16d78ca464db5364441f1565977
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