The secreted endoribonuclease ENDU-2 from the soma protects germline immortality in C. elegans

The question as to how the soma regulates the germline has been much studied. Here, the authors show in C. elegans that the poly-U specific endoribonuclease ENDU-2 is secreted from the soma and taken-up by the germline, binding mature mRNA, repressing expression of somatic transcripts and maintainin...

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Bibliographic Details
Main Authors: Wenjing Qi, Erika D. V. Gromoff, Fan Xu, Qian Zhao, Wei Yang, Dietmar Pfeifer, Wolfgang Maier, Lijiang Long, Ralf Baumeister
Format: article
Language:EN
Published: Nature Portfolio 2021
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Online Access:https://doaj.org/article/fd6af941845e499489ea04b3d6fe0d66
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