Cardiomyopathies in China: A 2018–2019 state-of-the-art review
Cardiomyopathies are diseases of the cardiac muscle and are often characterized by ventricular dilation, hypertrophy, and cardiac arrhythmia. Patients with cardiomyopathies often experience sudden death and cardiac failure and require cardiac transplantation during the course of disease progression....
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KeAi Communications Co., Ltd.
2020
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oai:doaj.org-article:fd6b673fb7f84a53a24f7242b320fe6e2021-12-02T13:57:40ZCardiomyopathies in China: A 2018–2019 state-of-the-art review2095-882X10.1016/j.cdtm.2020.05.006https://doaj.org/article/fd6b673fb7f84a53a24f7242b320fe6e2020-12-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S2095882X20300451https://doaj.org/toc/2095-882XCardiomyopathies are diseases of the cardiac muscle and are often characterized by ventricular dilation, hypertrophy, and cardiac arrhythmia. Patients with cardiomyopathies often experience sudden death and cardiac failure and require cardiac transplantation during the course of disease progression. Early diagnosis, differential diagnosis, and genetic consultation depend on imaging techniques, genetic testing, and new emerging diagnostic tools such as serum biomarkers. The molecular genetics of cardiomyopathies has been widely studied recently. The discovery of mechanisms underlying heterogeneity and overlapping of the phenotypes of cardiomyopathies has revealed the existence of disease modifiers, and this has led to the emergence of novel disease-modifying therapy. This 2018–2019 state-of-the-art review outlines the pathogenesis, diagnosis, and treatment of cardiomyopathies in China.Tian-Rui HuaShu-Yang ZhangKeAi Communications Co., Ltd.articleCardiomyopathiesGeneticsHeart failureMedicine (General)R5-920ENChronic Diseases and Translational Medicine, Vol 6, Iss 4, Pp 224-238 (2020) |
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Cardiomyopathies Genetics Heart failure Medicine (General) R5-920 |
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Cardiomyopathies Genetics Heart failure Medicine (General) R5-920 Tian-Rui Hua Shu-Yang Zhang Cardiomyopathies in China: A 2018–2019 state-of-the-art review |
description |
Cardiomyopathies are diseases of the cardiac muscle and are often characterized by ventricular dilation, hypertrophy, and cardiac arrhythmia. Patients with cardiomyopathies often experience sudden death and cardiac failure and require cardiac transplantation during the course of disease progression. Early diagnosis, differential diagnosis, and genetic consultation depend on imaging techniques, genetic testing, and new emerging diagnostic tools such as serum biomarkers. The molecular genetics of cardiomyopathies has been widely studied recently. The discovery of mechanisms underlying heterogeneity and overlapping of the phenotypes of cardiomyopathies has revealed the existence of disease modifiers, and this has led to the emergence of novel disease-modifying therapy. This 2018–2019 state-of-the-art review outlines the pathogenesis, diagnosis, and treatment of cardiomyopathies in China. |
format |
article |
author |
Tian-Rui Hua Shu-Yang Zhang |
author_facet |
Tian-Rui Hua Shu-Yang Zhang |
author_sort |
Tian-Rui Hua |
title |
Cardiomyopathies in China: A 2018–2019 state-of-the-art review |
title_short |
Cardiomyopathies in China: A 2018–2019 state-of-the-art review |
title_full |
Cardiomyopathies in China: A 2018–2019 state-of-the-art review |
title_fullStr |
Cardiomyopathies in China: A 2018–2019 state-of-the-art review |
title_full_unstemmed |
Cardiomyopathies in China: A 2018–2019 state-of-the-art review |
title_sort |
cardiomyopathies in china: a 2018–2019 state-of-the-art review |
publisher |
KeAi Communications Co., Ltd. |
publishDate |
2020 |
url |
https://doaj.org/article/fd6b673fb7f84a53a24f7242b320fe6e |
work_keys_str_mv |
AT tianruihua cardiomyopathiesinchinaa20182019stateoftheartreview AT shuyangzhang cardiomyopathiesinchinaa20182019stateoftheartreview |
_version_ |
1718392297682370560 |