A new molecular classification to drive precision treatment strategies in primary Sjögren’s syndrome

Sjögren’s syndrome, a disease that primarily affects women, is poorly understood. Here, the authors combine data from a large cohort of patients and healthy controls to identify biomarkers that distinguish patient subgroups to improve our understanding of the disease and facilitate drug development....

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Autores principales: Perrine Soret, Christelle Le Dantec, Emiko Desvaux, Nathan Foulquier, Bastien Chassagnol, Sandra Hubert, Christophe Jamin, Guillermo Barturen, Guillaume Desachy, Valérie Devauchelle-Pensec, Cheïma Boudjeniba, Divi Cornec, Alain Saraux, Sandrine Jousse-Joulin, Nuria Barbarroja, Ignasi Rodríguez-Pintó, Ellen De Langhe, Lorenzo Beretta, Carlo Chizzolini, László Kovács, Torsten Witte, PRECISESADS Clinical Consortium, PRECISESADS Flow Cytometry Consortium, Eléonore Bettacchioli, Anne Buttgereit, Zuzanna Makowska, Ralf Lesche, Maria Orietta Borghi, Javier Martin, Sophie Courtade-Gaiani, Laura Xuereb, Mickaël Guedj, Philippe Moingeon, Marta E. Alarcón-Riquelme, Laurence Laigle, Jacques-Olivier Pers
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Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/fd749685034f43a3afc45a40aaefddd7
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spelling oai:doaj.org-article:fd749685034f43a3afc45a40aaefddd72021-12-02T17:47:58ZA new molecular classification to drive precision treatment strategies in primary Sjögren’s syndrome10.1038/s41467-021-23472-72041-1723https://doaj.org/article/fd749685034f43a3afc45a40aaefddd72021-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-23472-7https://doaj.org/toc/2041-1723Sjögren’s syndrome, a disease that primarily affects women, is poorly understood. Here, the authors combine data from a large cohort of patients and healthy controls to identify biomarkers that distinguish patient subgroups to improve our understanding of the disease and facilitate drug development.Perrine SoretChristelle Le DantecEmiko DesvauxNathan FoulquierBastien ChassagnolSandra HubertChristophe JaminGuillermo BarturenGuillaume DesachyValérie Devauchelle-PensecCheïma BoudjenibaDivi CornecAlain SarauxSandrine Jousse-JoulinNuria BarbarrojaIgnasi Rodríguez-PintóEllen De LangheLorenzo BerettaCarlo ChizzoliniLászló KovácsTorsten WittePRECISESADS Clinical ConsortiumPRECISESADS Flow Cytometry ConsortiumEléonore BettacchioliAnne ButtgereitZuzanna MakowskaRalf LescheMaria Orietta BorghiJavier MartinSophie Courtade-GaianiLaura XuerebMickaël GuedjPhilippe MoingeonMarta E. Alarcón-RiquelmeLaurence LaigleJacques-Olivier PersNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Perrine Soret
Christelle Le Dantec
Emiko Desvaux
Nathan Foulquier
Bastien Chassagnol
Sandra Hubert
Christophe Jamin
Guillermo Barturen
Guillaume Desachy
Valérie Devauchelle-Pensec
Cheïma Boudjeniba
Divi Cornec
Alain Saraux
Sandrine Jousse-Joulin
Nuria Barbarroja
Ignasi Rodríguez-Pintó
Ellen De Langhe
Lorenzo Beretta
Carlo Chizzolini
László Kovács
Torsten Witte
PRECISESADS Clinical Consortium
PRECISESADS Flow Cytometry Consortium
Eléonore Bettacchioli
Anne Buttgereit
Zuzanna Makowska
Ralf Lesche
Maria Orietta Borghi
Javier Martin
Sophie Courtade-Gaiani
Laura Xuereb
Mickaël Guedj
Philippe Moingeon
Marta E. Alarcón-Riquelme
Laurence Laigle
Jacques-Olivier Pers
A new molecular classification to drive precision treatment strategies in primary Sjögren’s syndrome
description Sjögren’s syndrome, a disease that primarily affects women, is poorly understood. Here, the authors combine data from a large cohort of patients and healthy controls to identify biomarkers that distinguish patient subgroups to improve our understanding of the disease and facilitate drug development.
format article
author Perrine Soret
Christelle Le Dantec
Emiko Desvaux
Nathan Foulquier
Bastien Chassagnol
Sandra Hubert
Christophe Jamin
Guillermo Barturen
Guillaume Desachy
Valérie Devauchelle-Pensec
Cheïma Boudjeniba
Divi Cornec
Alain Saraux
Sandrine Jousse-Joulin
Nuria Barbarroja
Ignasi Rodríguez-Pintó
Ellen De Langhe
Lorenzo Beretta
Carlo Chizzolini
László Kovács
Torsten Witte
PRECISESADS Clinical Consortium
PRECISESADS Flow Cytometry Consortium
Eléonore Bettacchioli
Anne Buttgereit
Zuzanna Makowska
Ralf Lesche
Maria Orietta Borghi
Javier Martin
Sophie Courtade-Gaiani
Laura Xuereb
Mickaël Guedj
Philippe Moingeon
Marta E. Alarcón-Riquelme
Laurence Laigle
Jacques-Olivier Pers
author_facet Perrine Soret
Christelle Le Dantec
Emiko Desvaux
Nathan Foulquier
Bastien Chassagnol
Sandra Hubert
Christophe Jamin
Guillermo Barturen
Guillaume Desachy
Valérie Devauchelle-Pensec
Cheïma Boudjeniba
Divi Cornec
Alain Saraux
Sandrine Jousse-Joulin
Nuria Barbarroja
Ignasi Rodríguez-Pintó
Ellen De Langhe
Lorenzo Beretta
Carlo Chizzolini
László Kovács
Torsten Witte
PRECISESADS Clinical Consortium
PRECISESADS Flow Cytometry Consortium
Eléonore Bettacchioli
Anne Buttgereit
Zuzanna Makowska
Ralf Lesche
Maria Orietta Borghi
Javier Martin
Sophie Courtade-Gaiani
Laura Xuereb
Mickaël Guedj
Philippe Moingeon
Marta E. Alarcón-Riquelme
Laurence Laigle
Jacques-Olivier Pers
author_sort Perrine Soret
title A new molecular classification to drive precision treatment strategies in primary Sjögren’s syndrome
title_short A new molecular classification to drive precision treatment strategies in primary Sjögren’s syndrome
title_full A new molecular classification to drive precision treatment strategies in primary Sjögren’s syndrome
title_fullStr A new molecular classification to drive precision treatment strategies in primary Sjögren’s syndrome
title_full_unstemmed A new molecular classification to drive precision treatment strategies in primary Sjögren’s syndrome
title_sort new molecular classification to drive precision treatment strategies in primary sjögren’s syndrome
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/fd749685034f43a3afc45a40aaefddd7
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