Adverse eff ects of polymeric nanoparticle poly(ethylene glycol)- block-polylactide methyl ether (PEG-b-PLA) on steroid hormone secretion by porcine granulosa cells

Objectives. Development of nanoparticles (NPs) for biomedical applications, including medical imaging and drug delivery, is currently undergoing a dramatic expansion. Diverse effects of different type NPs relating to mammalian reproductive tissues have been demonstrated. Th e objective of this study...

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Autores principales:	Scsukova Sona, Bujnakova Mlynarcikova A., Kiss A., Rollerova E.
Formato:	article
Lenguaje:	EN
Publicado:	Sciendo 2017
Materias:	polymeric nanoparticles reproductive nanotoxicology steroidogenesis granulosa cells Diseases of the endocrine glands. Clinical endocrinology RC648-665
Acceso en línea:	https://doaj.org/article/fd78d8cd47f94ceaa18a38e6ec9d8e47
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spelling	oai:doaj.org-article:fd78d8cd47f94ceaa18a38e6ec9d8e472021-12-02T15:29:47ZAdverse eff ects of polymeric nanoparticle poly(ethylene glycol)- block-polylactide methyl ether (PEG-b-PLA) on steroid hormone secretion by porcine granulosa cells1336-032910.1515/enr-2017-0009https://doaj.org/article/fd78d8cd47f94ceaa18a38e6ec9d8e472017-04-01T00:00:00Zhttps://doi.org/10.1515/enr-2017-0009https://doaj.org/toc/1336-0329Objectives. Development of nanoparticles (NPs) for biomedical applications, including medical imaging and drug delivery, is currently undergoing a dramatic expansion. Diverse effects of different type NPs relating to mammalian reproductive tissues have been demonstrated. Th e objective of this study was to explore the in vitro effects of polymeric nanoparticle poly(ethylene glycol)-blockpolylactide methyl ether (PEG-b-PLA NPs) on functional state and viability of ovarian granulosa cells (GCs), which play an important role in maintaining ovarian function and female fertility.Scsukova SonaBujnakova Mlynarcikova A.Kiss A.Rollerova E.Sciendoarticlepolymeric nanoparticlesreproductive nanotoxicologysteroidogenesisgranulosa cellsDiseases of the endocrine glands. Clinical endocrinologyRC648-665ENEndocrine Regulations, Vol 51, Iss 2, Pp 96-104 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	polymeric nanoparticles reproductive nanotoxicology steroidogenesis granulosa cells Diseases of the endocrine glands. Clinical endocrinology RC648-665
spellingShingle	polymeric nanoparticles reproductive nanotoxicology steroidogenesis granulosa cells Diseases of the endocrine glands. Clinical endocrinology RC648-665 Scsukova Sona Bujnakova Mlynarcikova A. Kiss A. Rollerova E. Adverse eff ects of polymeric nanoparticle poly(ethylene glycol)- block-polylactide methyl ether (PEG-b-PLA) on steroid hormone secretion by porcine granulosa cells
description	Objectives. Development of nanoparticles (NPs) for biomedical applications, including medical imaging and drug delivery, is currently undergoing a dramatic expansion. Diverse effects of different type NPs relating to mammalian reproductive tissues have been demonstrated. Th e objective of this study was to explore the in vitro effects of polymeric nanoparticle poly(ethylene glycol)-blockpolylactide methyl ether (PEG-b-PLA NPs) on functional state and viability of ovarian granulosa cells (GCs), which play an important role in maintaining ovarian function and female fertility.
format	article
author	Scsukova Sona Bujnakova Mlynarcikova A. Kiss A. Rollerova E.
author_facet	Scsukova Sona Bujnakova Mlynarcikova A. Kiss A. Rollerova E.
author_sort	Scsukova Sona
title	Adverse eff ects of polymeric nanoparticle poly(ethylene glycol)- block-polylactide methyl ether (PEG-b-PLA) on steroid hormone secretion by porcine granulosa cells
title_short	Adverse eff ects of polymeric nanoparticle poly(ethylene glycol)- block-polylactide methyl ether (PEG-b-PLA) on steroid hormone secretion by porcine granulosa cells
title_full	Adverse eff ects of polymeric nanoparticle poly(ethylene glycol)- block-polylactide methyl ether (PEG-b-PLA) on steroid hormone secretion by porcine granulosa cells
title_fullStr	Adverse eff ects of polymeric nanoparticle poly(ethylene glycol)- block-polylactide methyl ether (PEG-b-PLA) on steroid hormone secretion by porcine granulosa cells
title_full_unstemmed	Adverse eff ects of polymeric nanoparticle poly(ethylene glycol)- block-polylactide methyl ether (PEG-b-PLA) on steroid hormone secretion by porcine granulosa cells
title_sort	adverse eff ects of polymeric nanoparticle poly(ethylene glycol)- block-polylactide methyl ether (peg-b-pla) on steroid hormone secretion by porcine granulosa cells
publisher	Sciendo
publishDate	2017
url	https://doaj.org/article/fd78d8cd47f94ceaa18a38e6ec9d8e47
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Adverse eff ects of polymeric nanoparticle poly(ethylene glycol)- block-polylactide methyl ether (PEG-b-PLA) on steroid hormone secretion by porcine granulosa cells

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