Current Knowledge About the Implication of Bacterial Microbiota in Human Health and Disease

Recent advances in molecular genetics and the invention of new technologies led to a development in our knowledge about human microbiota, specifically bacterial one. The microbiota plays a fundamental role in the immunologic, hormonal and metabolic homeostasis of the host. After the initiation of th...

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Autor principal:	Nikolova D.
Formato:	article
Lenguaje:	EN
Publicado:	Sciendo 2021
Materias:	microbiome microbiota bacteria human diseases Medicine R
Acceso en línea:	https://doaj.org/article/fd7f5075172b4f2990de313ed82998d7
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spelling	oai:doaj.org-article:fd7f5075172b4f2990de313ed82998d72021-12-05T14:11:05ZCurrent Knowledge About the Implication of Bacterial Microbiota in Human Health and Disease2719-538410.2478/amb-2021-0047https://doaj.org/article/fd7f5075172b4f2990de313ed82998d72021-11-01T00:00:00Zhttps://doi.org/10.2478/amb-2021-0047https://doaj.org/toc/2719-5384Recent advances in molecular genetics and the invention of new technologies led to a development in our knowledge about human microbiota, specifically bacterial one. The microbiota plays a fundamental role in the immunologic, hormonal and metabolic homeostasis of the host. After the initiation of the Human Microbiome Project, it became clear that the human microbiota consists of the 10-100 trillion symbiotic microbial cells harbored by each person, primarily bacteria in the gut, but also in other spots as the skin, mouth, nose, and vagina. Despite of the differences in studying bacterial species, decreased bacterial diversity and persistence has been connected with several diverse human diseases primarily diabetes, IBD (inflammatory bowel disease) and others; attempts were made even to explain psychiatric pathology. Several species emerged as dominant and were clearly linked to certain disorders or accepted as biomarkers of others. The current review aims to discuss key issues of our current knowledge about bacteria in human, the difficulties and methods of its analysis, its contribution to human health and responsibility for human diseases.Nikolova D.Sciendoarticlemicrobiomemicrobiotabacteriahuman diseasesMedicineRENActa Medica Bulgarica, Vol 48, Iss 4, Pp 43-49 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	microbiome microbiota bacteria human diseases Medicine R
spellingShingle	microbiome microbiota bacteria human diseases Medicine R Nikolova D. Current Knowledge About the Implication of Bacterial Microbiota in Human Health and Disease
description	Recent advances in molecular genetics and the invention of new technologies led to a development in our knowledge about human microbiota, specifically bacterial one. The microbiota plays a fundamental role in the immunologic, hormonal and metabolic homeostasis of the host. After the initiation of the Human Microbiome Project, it became clear that the human microbiota consists of the 10-100 trillion symbiotic microbial cells harbored by each person, primarily bacteria in the gut, but also in other spots as the skin, mouth, nose, and vagina. Despite of the differences in studying bacterial species, decreased bacterial diversity and persistence has been connected with several diverse human diseases primarily diabetes, IBD (inflammatory bowel disease) and others; attempts were made even to explain psychiatric pathology. Several species emerged as dominant and were clearly linked to certain disorders or accepted as biomarkers of others. The current review aims to discuss key issues of our current knowledge about bacteria in human, the difficulties and methods of its analysis, its contribution to human health and responsibility for human diseases.
format	article
author	Nikolova D.
author_facet	Nikolova D.
author_sort	Nikolova D.
title	Current Knowledge About the Implication of Bacterial Microbiota in Human Health and Disease
title_short	Current Knowledge About the Implication of Bacterial Microbiota in Human Health and Disease
title_full	Current Knowledge About the Implication of Bacterial Microbiota in Human Health and Disease
title_fullStr	Current Knowledge About the Implication of Bacterial Microbiota in Human Health and Disease
title_full_unstemmed	Current Knowledge About the Implication of Bacterial Microbiota in Human Health and Disease
title_sort	current knowledge about the implication of bacterial microbiota in human health and disease
publisher	Sciendo
publishDate	2021
url	https://doaj.org/article/fd7f5075172b4f2990de313ed82998d7
work_keys_str_mv	AT nikolovad currentknowledgeabouttheimplicationofbacterialmicrobiotainhumanhealthanddisease
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Current Knowledge About the Implication of Bacterial Microbiota in Human Health and Disease

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