Hypoxia changes the expression of the epidermal growth factor (EGF) system in human hearts and cultured cardiomyocytes.
<h4>Background</h4>The epidermal growth factor (EGF) receptors HER2 and HER4 and the ligands HB-EGF and NRG1 are crucial for heart development. The purpose of our study was to investigate the role of the complete EGF system in relation to hypoxia of the heart.<h4>Methodology/princi...
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Autores principales: | Mathias Munk, Ashfaque Ahmed Memon, Jens Peter Goetze, Lars Bo Nielsen, Ebba Nexo, Boe Sandahl Sorensen |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2012
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Materias: | |
Acceso en línea: | https://doaj.org/article/fd83521d64084aa0b6923d0e45dbbaae |
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