The small GTPase Rheb affects central brain neuronal morphology and memory formation in Drosophila.
Mutations in either of two tumor suppressor genes, TSC1 or TSC2, cause tuberous sclerosis complex (TSC), a syndrome resulting in benign hamartomatous tumors and neurological disorders. Cellular growth defects and neuronal disorganization associated with TSC are believed to be due to upregulated TOR...
Guardado en:
Autores principales: | Heather L D Brown, Karla R Kaun, Bruce A Edgar |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2012
|
Materias: | |
Acceso en línea: | https://doaj.org/article/fd843a34af0f4aec8908c40bea69ca89 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
14-3-3 proteins regulate Tctp–Rheb interaction for organ growth in Drosophila
por: Thao Phuong Le, et al.
Publicado: (2016) - Small GTPases
-
A small molecule inhibitor of Rheb selectively targets mTORC1 signaling
por: Sarah J. Mahoney, et al.
Publicado: (2018) -
Affecting long-term fear memory formation through optical control of Rac1 GTPase and PAK activity in lateral amygdala
por: Aniruddha Das, et al.
Publicado: (2017) -
Exercise modulates redox-sensitive small GTPase activity in the brain microvasculature in a model of brain metastasis formation.
por: Gretchen Wolff, et al.
Publicado: (2014)