Organoprotecive effects of angiotensin II receptor blockers in patients with type 2 diabetes mellitus

High prevalence of arterial hypertension and related cardiovascular complications dictates the necessity of preparations possessed of markedorganoprotective activity and good tolerability. The currently available data suggest advantages of iACE and ARB as preparations for the treatmentof cardiovascu...

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Autores principales: Ivona Yanovna Yarek-Martynova, Minara Shamkhalovna Shamkhalova
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RU
Publicado: Endocrinology Research Centre 2010
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Acceso en línea:https://doaj.org/article/fd87b527978f40e1b8fff9607c0aa113
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spelling oai:doaj.org-article:fd87b527978f40e1b8fff9607c0aa1132021-11-14T09:00:15ZOrganoprotecive effects of angiotensin II receptor blockers in patients with type 2 diabetes mellitus2072-03512072-037810.14341/2072-0351-5675https://doaj.org/article/fd87b527978f40e1b8fff9607c0aa1132010-06-01T00:00:00Zhttps://www.dia-endojournals.ru/jour/article/view/5675https://doaj.org/toc/2072-0351https://doaj.org/toc/2072-0378High prevalence of arterial hypertension and related cardiovascular complications dictates the necessity of preparations possessed of markedorganoprotective activity and good tolerability. The currently available data suggest advantages of iACE and ARB as preparations for the treatmentof cardiovascular diseases such as ability of iACE to improve clinical picture and outcome of therapy of cardiac insufficiency, left ventricle dysfunction,and myocardial infarction. Large-scale prospective studies demonstrated effectiveness of these agents in the treatment of CHD, stroke, diabetes, renalpathology and revealed their additional advantages attributable to inhibition of angiotensin II secretion other than those related to reduction of AP.These studies gave evidence of a more pronounced decrease in the frequency of cardiovascular events under effect of ARB in high-risk patients. However,protective action of ARB on the cardiovascular system compared with that of iACE and combination of ARB+iACE awaits an in-depth study.Ivona Yanovna Yarek-MartynovaMinara Shamkhalovna ShamkhalovaEndocrinology Research Centrearticletelmisartanangiotensin iiontargettranscendNutritional diseases. Deficiency diseasesRC620-627ENRUСахарный диабет, Vol 13, Iss 2, Pp 58-61 (2010)
institution DOAJ
collection DOAJ
language EN
RU
topic telmisartan
angiotensin ii
ontarget
transcend
Nutritional diseases. Deficiency diseases
RC620-627
spellingShingle telmisartan
angiotensin ii
ontarget
transcend
Nutritional diseases. Deficiency diseases
RC620-627
Ivona Yanovna Yarek-Martynova
Minara Shamkhalovna Shamkhalova
Organoprotecive effects of angiotensin II receptor blockers in patients with type 2 diabetes mellitus
description High prevalence of arterial hypertension and related cardiovascular complications dictates the necessity of preparations possessed of markedorganoprotective activity and good tolerability. The currently available data suggest advantages of iACE and ARB as preparations for the treatmentof cardiovascular diseases such as ability of iACE to improve clinical picture and outcome of therapy of cardiac insufficiency, left ventricle dysfunction,and myocardial infarction. Large-scale prospective studies demonstrated effectiveness of these agents in the treatment of CHD, stroke, diabetes, renalpathology and revealed their additional advantages attributable to inhibition of angiotensin II secretion other than those related to reduction of AP.These studies gave evidence of a more pronounced decrease in the frequency of cardiovascular events under effect of ARB in high-risk patients. However,protective action of ARB on the cardiovascular system compared with that of iACE and combination of ARB+iACE awaits an in-depth study.
format article
author Ivona Yanovna Yarek-Martynova
Minara Shamkhalovna Shamkhalova
author_facet Ivona Yanovna Yarek-Martynova
Minara Shamkhalovna Shamkhalova
author_sort Ivona Yanovna Yarek-Martynova
title Organoprotecive effects of angiotensin II receptor blockers in patients with type 2 diabetes mellitus
title_short Organoprotecive effects of angiotensin II receptor blockers in patients with type 2 diabetes mellitus
title_full Organoprotecive effects of angiotensin II receptor blockers in patients with type 2 diabetes mellitus
title_fullStr Organoprotecive effects of angiotensin II receptor blockers in patients with type 2 diabetes mellitus
title_full_unstemmed Organoprotecive effects of angiotensin II receptor blockers in patients with type 2 diabetes mellitus
title_sort organoprotecive effects of angiotensin ii receptor blockers in patients with type 2 diabetes mellitus
publisher Endocrinology Research Centre
publishDate 2010
url https://doaj.org/article/fd87b527978f40e1b8fff9607c0aa113
work_keys_str_mv AT ivonayanovnayarekmartynova organoproteciveeffectsofangiotensiniireceptorblockersinpatientswithtype2diabetesmellitus
AT minarashamkhalovnashamkhalova organoproteciveeffectsofangiotensiniireceptorblockersinpatientswithtype2diabetesmellitus
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