The role of polygenic risk and susceptibility genes in breast cancer over the course of life
Identifying women at high risk of breast cancer has important implications for screening. Here, the authors demonstrate that polygenic risk scores improve breast cancer risk prediction in the population, in women with mutations in high-risk genes and in women with close relatives with the disease.
Guardado en:
Autores principales: | Nina Mars, Elisabeth Widén, Sini Kerminen, Tuomo Meretoja, Matti Pirinen, Pietro della Briotta Parolo, Priit Palta, FinnGen, Aarno Palotie, Jaakko Kaprio, Heikki Joensuu, Mark Daly, Samuli Ripatti |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2020
|
Materias: | |
Acceso en línea: | https://doaj.org/article/fd90f82ba68946fbb3ef19bfa8e2fc82 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Genetic architecture of human plasma lipidome and its link to cardiovascular disease
por: Rubina Tabassum, et al.
Publicado: (2019) -
Vesilaki uudistui - Miten se näkyy metsätaloudessa?
por: Samuli Joensuu
Publicado: (2013) -
Polygenic risk scores and rheumatic diseases
por: Matthew A. Brown, et al.
Publicado: (2021) -
Reaction Time and Visual Memory in Connection to Hazardous Drinking Polygenic Scores in Schizophrenia, Schizoaffective Disorder and Bipolar Disorder
por: Atiqul Haq Mazumder, et al.
Publicado: (2021) -
On cross-ancestry cancer polygenic risk scores.
por: Lars G Fritsche, et al.
Publicado: (2021)