Glycoprotein 2 is a specific cell surface marker of human pancreatic progenitors

Pancreatic progenitors (PPs) can be derived from human pluripotent stem cells in vitro but efficiency of differentiation varies, making it hard to sort for insulin-producing cells. Here, the authors use a proteomic approach to identify the secretory granule membrane glycoprotein 2 as a marker for PD...

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Autores principales:	Kathryn F. Cogger, Ankit Sinha, Farida Sarangi, Emily C. McGaugh, Diane Saunders, Craig Dorrell, Salvador Mejia-Guerrero, Yasaman Aghazadeh, Jillian L. Rourke, Robert A. Screaton, Markus Grompe, Philip R. Streeter, Alvin C. Powers, Marcela Brissova, Thomas Kislinger, M. Cristina Nostro
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/fd9272cedfac4963a9e8b1e7fd7c10ad
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spelling	oai:doaj.org-article:fd9272cedfac4963a9e8b1e7fd7c10ad2021-12-02T17:06:19ZGlycoprotein 2 is a specific cell surface marker of human pancreatic progenitors10.1038/s41467-017-00561-02041-1723https://doaj.org/article/fd9272cedfac4963a9e8b1e7fd7c10ad2017-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00561-0https://doaj.org/toc/2041-1723Pancreatic progenitors (PPs) can be derived from human pluripotent stem cells in vitro but efficiency of differentiation varies, making it hard to sort for insulin-producing cells. Here, the authors use a proteomic approach to identify the secretory granule membrane glycoprotein 2 as a marker for PDX1+/NKX6-1+ PPs.Kathryn F. CoggerAnkit SinhaFarida SarangiEmily C. McGaughDiane SaundersCraig DorrellSalvador Mejia-GuerreroYasaman AghazadehJillian L. RourkeRobert A. ScreatonMarkus GrompePhilip R. StreeterAlvin C. PowersMarcela BrissovaThomas KislingerM. Cristina NostroNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Kathryn F. Cogger Ankit Sinha Farida Sarangi Emily C. McGaugh Diane Saunders Craig Dorrell Salvador Mejia-Guerrero Yasaman Aghazadeh Jillian L. Rourke Robert A. Screaton Markus Grompe Philip R. Streeter Alvin C. Powers Marcela Brissova Thomas Kislinger M. Cristina Nostro Glycoprotein 2 is a specific cell surface marker of human pancreatic progenitors
description	Pancreatic progenitors (PPs) can be derived from human pluripotent stem cells in vitro but efficiency of differentiation varies, making it hard to sort for insulin-producing cells. Here, the authors use a proteomic approach to identify the secretory granule membrane glycoprotein 2 as a marker for PDX1+/NKX6-1+ PPs.
format	article
author	Kathryn F. Cogger Ankit Sinha Farida Sarangi Emily C. McGaugh Diane Saunders Craig Dorrell Salvador Mejia-Guerrero Yasaman Aghazadeh Jillian L. Rourke Robert A. Screaton Markus Grompe Philip R. Streeter Alvin C. Powers Marcela Brissova Thomas Kislinger M. Cristina Nostro
author_facet	Kathryn F. Cogger Ankit Sinha Farida Sarangi Emily C. McGaugh Diane Saunders Craig Dorrell Salvador Mejia-Guerrero Yasaman Aghazadeh Jillian L. Rourke Robert A. Screaton Markus Grompe Philip R. Streeter Alvin C. Powers Marcela Brissova Thomas Kislinger M. Cristina Nostro
author_sort	Kathryn F. Cogger
title	Glycoprotein 2 is a specific cell surface marker of human pancreatic progenitors
title_short	Glycoprotein 2 is a specific cell surface marker of human pancreatic progenitors
title_full	Glycoprotein 2 is a specific cell surface marker of human pancreatic progenitors
title_fullStr	Glycoprotein 2 is a specific cell surface marker of human pancreatic progenitors
title_full_unstemmed	Glycoprotein 2 is a specific cell surface marker of human pancreatic progenitors
title_sort	glycoprotein 2 is a specific cell surface marker of human pancreatic progenitors
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/fd9272cedfac4963a9e8b1e7fd7c10ad
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Glycoprotein 2 is a specific cell surface marker of human pancreatic progenitors

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