The transcriptomic signature of RacA activation and inactivation provides new insights into the morphogenetic network of Aspergillus niger.

The transcriptomic signature of RacA activation and inactivation provides new insights into the morphogenetic network of Aspergillus niger.

RacA is the main Rho GTPase in Aspergillus niger regulating polarity maintenance via controlling actin dynamics. Both deletion and dominant activation of RacA (Rac(G18V)) provoke an actin localization defect and thereby loss of polarized tip extension, resulting in frequent dichotomous branching in...

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Autores principales: Min Jin Kwon, Benjamin M Nitsche, Mark Arentshorst, Thomas R Jørgensen, Arthur F J Ram, Vera Meyer
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/fd9347551bcf463fb43a9d9e8bfbdd40
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