Effects of functional variants of vitamin C transporter genes on apolipoprotein E E4-associated risk of cognitive decline: The Nakajima study

Effects of functional variants of vitamin C transporter genes on apolipoprotein E E4-associated risk of cognitive decline: The Nakajima study

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Apolipoprotein E E4 (APOE4) is a risk factor for cognitive decline. A high blood vitamin C (VC) level reduces APOE4-associated risk of developing cognitive decline in women. In the present study, we aimed to examine the effects of functional variants of VC transporter genes expressed in the brain (S...

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Autores principales: Koji Hayashi, Moeko Noguchi-Shinohara, Takehiro Sato, Kazuyoshi Hosomichi, Takayuki Kannon, Chiemi Abe, Chiaki Domoto, Sohshi Yuki-Nozaki, Ayaka Mori, Mai Horimoto, Masami Yokogawa, Kenji Sakai, Kazuo Iwasa, Kiyonobu Komai, Mai Ishimiya, Hiroyuki Nakamura, Natsuko Ishida, Yukio Suga, Junko Ishizaki, Akihito Ishigami, Atsushi Tajima, Masahito Yamada
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2021
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/fd9732df1c6744229aa08b2ca9353a01
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