Innate-like self-reactive B cells infiltrate human renal allografts during transplant rejection

Intrarenal B cells are indicative of poor prognosis in human renal allografts. Here the authors use single cell RNA sequencing to examine how intrarenal B cells contribute to renal rejection and find a population of innate B cells reactive to renal-specific or inflammation-associated antigens.

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Autores principales:	Yuta Asano, Joe Daccache, Dharmendra Jain, Kichul Ko, Andrew Kinloch, Margaret Veselits, Donald Wolfgeher, Anthony Chang, Michelle Josephson, Patrick Cunningham, Anat Tambur, Aly A. Khan, Shiv Pillai, Anita S. Chong, Marcus R. Clark
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/fda8e4a80e2a40b1a77ed6fa113be6ca
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spelling	oai:doaj.org-article:fda8e4a80e2a40b1a77ed6fa113be6ca2021-12-02T15:33:16ZInnate-like self-reactive B cells infiltrate human renal allografts during transplant rejection10.1038/s41467-021-24615-62041-1723https://doaj.org/article/fda8e4a80e2a40b1a77ed6fa113be6ca2021-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-24615-6https://doaj.org/toc/2041-1723Intrarenal B cells are indicative of poor prognosis in human renal allografts. Here the authors use single cell RNA sequencing to examine how intrarenal B cells contribute to renal rejection and find a population of innate B cells reactive to renal-specific or inflammation-associated antigens.Yuta AsanoJoe DaccacheDharmendra JainKichul KoAndrew KinlochMargaret VeselitsDonald WolfgeherAnthony ChangMichelle JosephsonPatrick CunninghamAnat TamburAly A. KhanShiv PillaiAnita S. ChongMarcus R. ClarkNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Yuta Asano Joe Daccache Dharmendra Jain Kichul Ko Andrew Kinloch Margaret Veselits Donald Wolfgeher Anthony Chang Michelle Josephson Patrick Cunningham Anat Tambur Aly A. Khan Shiv Pillai Anita S. Chong Marcus R. Clark Innate-like self-reactive B cells infiltrate human renal allografts during transplant rejection
description	Intrarenal B cells are indicative of poor prognosis in human renal allografts. Here the authors use single cell RNA sequencing to examine how intrarenal B cells contribute to renal rejection and find a population of innate B cells reactive to renal-specific or inflammation-associated antigens.
format	article
author	Yuta Asano Joe Daccache Dharmendra Jain Kichul Ko Andrew Kinloch Margaret Veselits Donald Wolfgeher Anthony Chang Michelle Josephson Patrick Cunningham Anat Tambur Aly A. Khan Shiv Pillai Anita S. Chong Marcus R. Clark
author_facet	Yuta Asano Joe Daccache Dharmendra Jain Kichul Ko Andrew Kinloch Margaret Veselits Donald Wolfgeher Anthony Chang Michelle Josephson Patrick Cunningham Anat Tambur Aly A. Khan Shiv Pillai Anita S. Chong Marcus R. Clark
author_sort	Yuta Asano
title	Innate-like self-reactive B cells infiltrate human renal allografts during transplant rejection
title_short	Innate-like self-reactive B cells infiltrate human renal allografts during transplant rejection
title_full	Innate-like self-reactive B cells infiltrate human renal allografts during transplant rejection
title_fullStr	Innate-like self-reactive B cells infiltrate human renal allografts during transplant rejection
title_full_unstemmed	Innate-like self-reactive B cells infiltrate human renal allografts during transplant rejection
title_sort	innate-like self-reactive b cells infiltrate human renal allografts during transplant rejection
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/fda8e4a80e2a40b1a77ed6fa113be6ca
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Innate-like self-reactive B cells infiltrate human renal allografts during transplant rejection

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