Innate-like self-reactive B cells infiltrate human renal allografts during transplant rejection
Intrarenal B cells are indicative of poor prognosis in human renal allografts. Here the authors use single cell RNA sequencing to examine how intrarenal B cells contribute to renal rejection and find a population of innate B cells reactive to renal-specific or inflammation-associated antigens.
Enregistré dans:
Auteurs principaux: | Yuta Asano, Joe Daccache, Dharmendra Jain, Kichul Ko, Andrew Kinloch, Margaret Veselits, Donald Wolfgeher, Anthony Chang, Michelle Josephson, Patrick Cunningham, Anat Tambur, Aly A. Khan, Shiv Pillai, Anita S. Chong, Marcus R. Clark |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2021
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/fda8e4a80e2a40b1a77ed6fa113be6ca |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
CHEMOKINE MARKERS ASSOCIATED WITH EARLY REJECTION OF KIDNEY ALLOGRAFT
par: T. V. Fedorenko, et autres
Publié: (2019) -
Immunological and regenerative aspects of hepatic mast cells in liver allograft rejection and tolerance.
par: Toshiaki Nakano, et autres
Publié: (2012) -
α1-Antitrypsin attenuates acute rejection of orthotopic murine lung allografts
par: Tomoyuki Nakagiri, et autres
Publié: (2021) -
Tacrolimus Blood Level Fluctuation Predisposes to Coexisting BK Virus Nephropathy and Acute Allograft Rejection
par: Chia-Lin Shen, et autres
Publié: (2017) -
The purinergic receptor antagonist oxidized adenosine triphosphate suppresses immune-mediated corneal allograft rejection
par: William Foulsham, et autres
Publié: (2019)