Stochastic master equation for early protein aggregation in the transthyretin amyloid disease

Abstract It is significant to understand the earliest molecular events occurring in the nucleation of the amyloid aggregation cascade for the prevention of amyloid related diseases such as transthyretin amyloid disease. We develop chemical master equation for the aggregation of monomers into oligome...

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Autores principales: Ruo-Nan Liu, Yan-Mei Kang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/fdada9857a73460eb14fb984d9f8549b
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